Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233802 | 0.78 | TLR8 (0.71) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL3229910 | 0.76 | MEN1 (0.54) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL3450738 | 0.71 | MEN1 (0.66) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL782567 | 0.70 | MEN1 (1.00) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL13510002 | 0.69 | HPGD (0.59) | ALDH1A1L3MBTL1HPGDKDM4ENPC1 | |
| SCHEMBL27873804 | 0.69 | TLR8 (0.62) | ALDH1A1HPGDSMN1; SMN2TLR8KDM4E | |
| Biphenyl SCHEMBL7742046 | 0.68 | SIGMAR1 (0.59) | ALDH1A1SMN1; SMN2KDM4EACP1 | |
| SCHEMBL21444460 | 0.68 | MEN1 (0.65) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| Ammonia Solution, Strong SCHEMBL28964330 | 0.67 | MAOA (0.69) | MEN1KMT2ASMN1; SMN2MAPTTDP1 | |
| SCHEMBL24212278 | 0.67 | MEN1 (0.91) | ALDH1A1L3MBTL1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | disclosed |