⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647055 | 0.83 | NOS3 (0.47) | — | |
| SCHEMBL7647057 | 0.77 | L3MBTL1 (0.50) | — | |
| SCHEMBL130894 | 0.75 | — | — | |
| SCHEMBL5174355 | 0.74 | HTR3E (0.58) | — | |
| SCHEMBL3284038 | 0.74 | HTR3E (0.58) | — | |
| SCHEMBL7646315 | 0.74 | HTR3E (0.44) | — | |
| SCHEMBL5512811 | 0.72 | NOS3 (0.45) | — | |
| SCHEMBL1871119 | 0.72 | — | — | |
| SCHEMBL7116305 | 0.71 | NOS3 (0.44) | — | |
| SCHEMBL5027177 | 0.71 | NOS3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068586-A2 | HIV/FIV PROTEASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-09-06 | — | — | WO | claimed |
| EP-0333080-B1 | BETA-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | claimed |
| US-5206254-A | Antitussive agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-04-27 | — | — | US | claimed |
| EP-0407403-A1 | BETA-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1991-01-16 | — | — | EP | claimed |
| WO-1989008648-A1 | beta-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-09-21 | — | — | WO | claimed |
| EP-0333080-A1 | Beta-carbonyl-carboxyamides of 1,3-thiazolidines | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-09-20 | — | — | EP | claimed |
| WO-2010002998-A1 | 2,4,6-TRISUBSTITUTED PYRIDO (3,2-d) PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| US-7223755-B2 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20050176704-A1 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| US-6476226-B2 | PLATELET GLYCOPROTEIN IIB/IIIA FIBRINOGEN; ANTICOAGULANTS; THROMBOLYTIC AGENTS; THROMBOEMBOLIC DISORDERS; ANTIINFLAMMATORY AGENTS; BONE DISORDERS; ANTITUMOR, -METASTASIS, -ARTHRITIC AGENTS; ASTHMA; PSORIASIS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-11-05 | — | — | US | disclosed |
| WO-2002068586-A2 | HIV/FIV PROTEASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-09-06 | — | — | WO | disclosed |
| US-6303609-B1 | USED FOR THE INHIBITION OF PLATELET AGGREGATION, AS THROMBOLYTICS, AND/OR FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2001-10-16 | — | — | US | disclosed |
| US-5273976-A | Ocular hypotensive agents | SANKYO COMPANY, LIMITED (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5175161-A | Treatment of glaucoma | SANKYO COMPANY, LIMITED (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0391721-A2 | Ocular hypotensive agents | Sankyo Company Limited (JP) | 1990-10-10 | — | — | EP | disclosed |