Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15421405 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2FDPSALDH1A1TDP1 | |
| SCHEMBL16615962 | 0.91 | ALDH1A1 (0.54) | LPAR3LPAR2FDPSALDH1A1TDP1 | |
| SCHEMBL8463447 | 0.82 | FDPS (0.42) | FDPSALDH1A1TDP1TYMSS1PR2 | |
| SCHEMBL19212013 | 0.78 | FDPS (0.64) | LPAR3LPAR2FDPSALDH1A1TDP1 | |
| SCHEMBL15995174 | 0.76 | LPAR3 (0.62) | LPAR3LPAR2FDPSS1PR2S1PR1 | |
| SCHEMBL1100535 | 0.76 | LPAR3 (0.56) | LPAR3LPAR2FDPSALDH1A1TDP1 | |
| SCHEMBL1101281 | 0.76 | LPAR3 (0.56) | LPAR3LPAR2FDPSALDH1A1TDP1 | |
| SCHEMBL1100677 | 0.76 | LPAR3 (0.56) | LPAR3LPAR2FDPSALDH1A1TDP1 | |
| SCHEMBL1100638 | 0.76 | LPAR3 (0.56) | LPAR3LPAR2FDPSALDH1A1TDP1 | |
| SCHEMBL1099485 | 0.76 | LPAR3 (0.56) | LPAR3LPAR2FDPSALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014526-A2 | CHEMICAL MODIFICATION OF NANOCRYSTAL SURFACES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-04 | — | — | WO | disclosed |