Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234252 | 0.91 | CHRM1 (0.44) | CHRM1MRGPRX4RORCP2RX7ICMT | |
| SCHEMBL3234250 | 0.87 | CHRM1 (0.59) | CHRM1MRGPRX4RORCCYP3A4CYP2C9 | |
| SCHEMBL3237454 | 0.87 | CHRM1 (0.41) | CHRM1MRGPRX4P2RX7TRAP1FFAR1 | |
| SCHEMBL3234237 | 0.86 | CHRM1 (0.56) | CHRM1P2RX7POLBMAPTALDH1A1 | |
| SCHEMBL3234280 | 0.84 | CHRM1 (0.49) | CHRM1ICMTMAPTALDH1A1 | |
| SCHEMBL3236068 | 0.83 | CHRM1 (0.51) | CHRM1RORCP2RX7CYP3A4CYP2C9 | |
| SCHEMBL3233936 | 0.82 | CHRM1 (0.46) | CHRM1P2RX7MAPT | |
| SCHEMBL3234282 | 0.81 | CHRM1 (0.47) | CHRM1RORCP2RX7POLBMAPT | |
| SCHEMBL3234297 | 0.81 | CHRM1 (0.48) | CHRM1RORCP2RX7ICMTMAPT | |
| SCHEMBL3235218 | 0.81 | CHRM1 (0.44) | CHRM1RORCP2RX7CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963271-B1 | QUINOLONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2010-07-28 | — | — | EP | claimed |