⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106439 | 0.79 | ITGB2 (0.30) | — | |
| SCHEMBL9174815 | 0.77 | — | — | |
| SCHEMBL106440 | 0.75 | ABCG2 (0.39) | — | |
| SCHEMBL26613407 | 0.71 | MAOA (0.31) | — | |
| SCHEMBL669443 | 0.69 | — | — | |
| SCHEMBL3417718 | 0.69 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL4239945 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL6762162 | 0.65 | MAOA (0.42) | — | |
| SCHEMBL2526305 | 0.65 | — | — | |
| SCHEMBL103524 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200288710-A1 | SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-09-17 | — | — | US | claimed |
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | claimed |
| US-10207985-B2 | Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-19 | — | — | US | claimed |
| EP-3429355-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | Bayer CropScience AG (DE) | 2019-01-23 | — | — | EP | claimed |
| WO-2017157735-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-21 | — | — | WO | claimed |
| US-9260448-B2 | Thienopyrimidinone derivatives as mGluR1 antagonists | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-02-16 | — | — | US | claimed |
| US-20140228565-A1 | THIENOPYRIMIDINONE DERIVATIVES AS mGluR1 ANTAGONISTS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-08-14 | — | — | US | claimed |
| EP-2486031-A2 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2012-08-15 | — | — | EP | claimed |
| WO-2011042389-A2 | PHENYLPYRI(MI)DINYLAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | WO | claimed |
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-111936487-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-112312909-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113412112-B | Organophosphorus substituted compounds as c-MET inhibitors and therapeutic uses thereof | 贝达医药公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| EP-1194416-A1 | HALOPYRIMIDINES | Bayer Aktiengesellschaft (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-6294659-B1 | NUCLEOSIDE ANALOG THAT CAN BE ENZYMATICALLY INCORPORATED INTO A NUCLEIC ACID CHAIN AND THEN ACTIVATED FOR CLEAVAGE OF THAT CHAIN | DUKE UNIVERSITY | 2001-09-25 | — | — | US | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078732-A1 | HALOPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000004036-A9 | PHOTOCLEAVABLE NUCLEOSIDE BASE | UNIV DUKE (US) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000004036-A1 | PHOTOCLEAVABLE NUCLEOSIDE BASE | DUKE UNIVERSITY (US) | 2000-01-27 | — | — | WO | disclosed |