⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277113 | 0.81 | — | — | |
| SCHEMBL395820 | 0.68 | MAOA (0.38) | — | |
| SCHEMBL323509 | 0.68 | — | — | |
| SCHEMBL13278933 | 0.66 | — | — | |
| SCHEMBL449729 | 0.65 | — | — | |
| SCHEMBL106439 | 0.65 | ITGB2 (0.30) | — | |
| SCHEMBL9174815 | 0.63 | — | — | |
| SCHEMBL4513586 | 0.63 | TSHR (0.31) | — | |
| SCHEMBL669443 | 0.60 | — | — | |
| SCHEMBL103524 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036455-A1 | ARYLPIPERAZINE DERIVATIVE AND USE THEREOF AS 5-HT1A RECEPTOR LIGANDS | CEPA SCHWARZ PHARMA, S.L. (ES) | 2009-02-05 | — | — | US | claimed |
| EP-1830854-A1 | ARYLPIPERAZINE DERIVATIVES AND USE THEREOF AS 5-HT1A RECEPTOR LIGANDS | Schwarz Pharma, s.l. (ES) | 2007-09-12 | — | — | EP | claimed |
| WO-2006069993-A1 | ARYLPIPERAZINE DERIVATIVES AND USE THEREOF AS 5-HT1A RECEPTOR LIGANDS | SCHWARZ PHARMA S.L. (ES) | 2006-07-06 | — | — | WO | claimed |
| EP-1674103-A1 | Arylpiperazine derivatives and use thereof as 5-HT1A receptor ligands | Cepa Schwarz Pharma s.l. (ES) | 2006-06-28 | — | — | EP | claimed |
| US-20090036455-A1 | ARYLPIPERAZINE DERIVATIVE AND USE THEREOF AS 5-HT1A RECEPTOR LIGANDS | CEPA SCHWARZ PHARMA, S.L. (ES) | 2009-02-05 | — | — | US | disclosed |
| EP-1830854-A1 | ARYLPIPERAZINE DERIVATIVES AND USE THEREOF AS 5-HT1A RECEPTOR LIGANDS | Schwarz Pharma, s.l. (ES) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006069993-A1 | ARYLPIPERAZINE DERIVATIVES AND USE THEREOF AS 5-HT1A RECEPTOR LIGANDS | SCHWARZ PHARMA S.L. (ES) | 2006-07-06 | — | — | WO | disclosed |
| EP-1674103-A1 | Arylpiperazine derivatives and use thereof as 5-HT1A receptor ligands | Cepa Schwarz Pharma s.l. (ES) | 2006-06-28 | — | — | EP | disclosed |