SCHEMBL3236372

SCHEMBL3236372

Cc1ccc(-c2nnc(-c3ccc(C)cc3N)o2)c(N)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.48
CA2 P00918 2/20 0.48
SMN1; SMN2 Q16637 7/20 0.46
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 2/20 0.46
ALOX15 P16050 2/20 0.46
CYP3A4 P08684 2/20 0.46
THRB P10828 1/20 0.46
ALDH1A1 P00352 6/20 0.45
NPC1 O15118 8/20 0.45
RAB9A P51151 8/20 0.45
HPGD P15428 5/20 0.45
HSD17B10 Q99714 2/20 0.45
POLB P06746 2/20 0.45
KDM4E B2RXH2 4/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
GAA P10253 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30839750 0.82 TDP1 (0.65) CA1SMN1; SMN2TDP1TP53ALOX15
SCHEMBL6365723 0.82 TDP1 (0.65) CA1SMN1; SMN2TDP1TP53ALOX15
SCHEMBL30839742 0.82 TDP1 (0.65) CA1SMN1; SMN2TDP1TP53ALOX15
Hydrochloric Acid SCHEMBL11683111 0.80 TDP1 (0.62) CA1SMN1; SMN2TDP1TP53ALOX15
SCHEMBL5550357 0.78 NOTUM (0.53) CA1CA2SMN1; SMN2TDP1TP53
SCHEMBL5505597 0.76 KDM4E (0.58) CA1CA2SMN1; SMN2TDP1TP53
SCHEMBL996798 0.74 KDM4E (0.41) CA1SMN1; SMN2TDP1TP53ALOX15
SCHEMBL6011538 0.74 CYP3A4 (0.54) CA1SMN1; SMN2TDP1TP53ALOX15
SCHEMBL424797 0.74 TDP1 (0.54) CA1SMN1; SMN2TDP1TP53ALOX15
SCHEMBL9154220 0.73 RAB9A (0.45) CA1CA2SMN1; SMN2TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109196426-A Electrophtography photosensor, handle box and image forming apparatus 京瓷办公信息系统株式会社 2019-01-11 CN disclosed
US-9023564-B2 Azoquinone compound, electrophotographic photoconductor, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-05-05 US disclosed
US-20140295335-A1 AZOQUINONE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2014-10-02 US disclosed
US-8765337-B2 Multilayer type electrophotographic photoconductor and image forming apparatus KYOCERA MITA CORPORATION (JP) 2014-07-01 US disclosed
US-7745081-B2 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2010-06-29 US disclosed
US-20080286673-A1 Single layer type electrophotographic photoconductor and image forming device KYOCERA MITA CORPORATION 2008-11-20 US disclosed
US-7416825-B2 Single layer type electrophotographic photoconductor and image forming device KYOCERA MITA CORPORATION (JP) 2008-08-26 US disclosed
US-20070281227-A1 Multilayer type electrophotographic photoconductor and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2007-12-06 US disclosed
US-20070275314-A1 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2007-11-29 US disclosed
US-20060160005-A1 Single layer type electrophotographic photoconductor and image forming device KYOCERA MITA CORPORATION (JP) 2006-07-20 US disclosed
EP-0390195-A1 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed