Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16025001 | 0.81 | CA1 (0.54) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL13017311 | 0.79 | CA1 (0.71) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL14424569 | 0.79 | CA1 (0.51) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL13170400 | 0.78 | RAB9A (0.74) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL24042623 | 0.76 | CA1 (0.49) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL22792080 | 0.76 | CA1 (0.49) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL3236372 | 0.76 | CA1 (0.48) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL97137 | 0.75 | CA1 (0.48) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL97136 | 0.75 | CA1 (0.51) | KDM4ECA1CA2NPC1RAB9A | |
| SCHEMBL6903361 | 0.73 | KDM4E (1.00) | KDM4ENPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8784782-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130071536-A1 | COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| EP-1850681-A2 | COMPOUNDS COMPRISING LINKED HETERO ARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | Senomyx, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
| US-20060263411-A1 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. | 2006-11-23 | — | — | US | disclosed |
| WO-2006084186-A2 | COMPOUNDS COMPRISING LINKED HETERO ARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060263411-A1 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | TAS2R46, TAS2R30, TAS2R50 | KDM4E 2906/4885CA1 3822/4885CA2 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.