SCHEMBL996798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11017014	0.82	NPC1 (0.46)	KDM4EMEN1NOS3NOS1NOS2
	SCHEMBL16521356	0.81	TRPA1 (0.42)	MEN1KMT2ATDP1ALOX15SMN1; SMN2
	SCHEMBL28759013	0.79	CFTR (0.39)	KMT2ACFTRBRD4CA1NPC1
	SCHEMBL22864466	0.79	BRD4 (0.38)	KDM4EMEN1NOS3NOS1NOS2
	SCHEMBL22187760	0.79	CTSA (0.44)	BRD4TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL3091622	0.79	CSNK1A1 (0.44)	KDM4ETDP1ALOX15CYP3A4SMN1; SMN2
	SCHEMBL1289874	0.79	ALDH1A1 (0.42)	KDM4EMEN1NOS3NOS1NOS2
	SCHEMBL13481179	0.77	IMPDH2 (0.49)	MEN1KMT2ACYP3A4SMN1; SMN2TP53
	SCHEMBL16423787	0.77	HPGDS (0.41)	KDM4ESMN1; SMN2ALDH1A1CFTRBRD4
	SCHEMBL3725066	0.76	BRD4 (0.38)	TDP1SMN1; SMN2TP53BRD4TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.