Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16589375 | 0.83 | FFAR1 (0.45) | FFAR1PPARGPPARA | |
| SCHEMBL17724503 | 0.82 | KDM4E (0.60) | KDM4EHDAC4HDAC7HDAC5CNR2 | |
| SCHEMBL17653645 | 0.81 | PPARA (0.49) | PPARGPPARALMNA | |
| SCHEMBL2553482 | 0.81 | PPARA (0.49) | PPARGPPARALMNA | |
| SCHEMBL6504745 | 0.81 | PPARA (0.49) | PPARGPPARALMNA | |
| SCHEMBL758770 | 0.81 | CPN1 (0.53) | PPARGPPARALMNA | |
| SCHEMBL6391032 | 0.81 | HDAC4 (0.41) | KDM4EHDAC4HDAC7HDAC5CNR2 | |
| SCHEMBL17295988 | 0.81 | GLS (0.42) | FFAR1MEN1KMT2APPARGPPARA | |
| SCHEMBL24327731 | 0.80 | HPGD (0.49) | MEN1KMT2APPARGPPARALMNA | |
| SCHEMBL17295981 | 0.80 | HPGD (0.49) | MEN1KMT2APPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015588-A1 | BENZYL-SUBSTITUTED TETRACYCLIC HETEROCYCLIC COMPOUNDS | NYCOMED GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |