SCHEMBL2553482

SCHEMBL2553482

CCOC(C(=O)O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 9/20 0.49
PPARG P37231 6/20 0.47
CYP2D6 P10635 2/20 0.45
SRC P12931 1/20 0.45
MMP8 P22894 1/20 0.45
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
POLB P06746 1/20 0.44
LMNA P02545 3/20 0.44
CYP1A2 P05177 1/20 0.44
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17653645 1.00 PPARA (0.49) PPARAPPARGCYP2D6SRCMMP8
SCHEMBL6504745 1.00 PPARA (0.49) PPARAPPARGCYP2D6SRCMMP8
SCHEMBL27688938 0.89 PTGS2 (0.53) PPARAPPARGALDH1A1CYP1A2
SCHEMBL13491149 0.86 ALDH1A1 (0.47) PPARAPPARGMMP8ALDH1A1CYP3A4
SCHEMBL6972548 0.86 MMP8 (0.44) PPARAPPARGMMP8ALDH1A1CYP3A4
SCHEMBL24327752 0.85 FFAR1 (0.47) PPARAPPARGALDH1A1POLBLMNA
SCHEMBL10355170 0.85 ESR1 (0.44) PPARACYP2D6SRCALDH1A1CYP3A4
SCHEMBL16672673 0.85 MMP8 (0.54) MMP8ALDH1A1LMNA
SCHEMBL5322346 0.85 ALDH1A1 (0.46) PPARAPPARGMMP8ALDH1A1CYP3A4
SCHEMBL17724542 0.85 PPARA (0.47) PPARAPPARGCYP2D6SRCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096421-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096419-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096425-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096418-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096417-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096420-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096424-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
EP-2687531-B1 TETRAHYDROCARBOLINE DERIVATIVE ONO PHARMACEUTICAL CO (JP) 2016-07-13 EP claimed
WO-2025074305-A1 N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-04-10 WO disclosed
CN-116348295-A Ultraviolet curable resin composition 电化株式会社 2023-06-27 CN disclosed
CN-116323200-A Ultraviolet curable resin composition 电化株式会社 2023-06-23 CN disclosed
CN-115594683-B Glutaminase GLS1 inhibitor and preparation method and application thereof 杭州禹胜医药科技有限公司 2023-06-16 CN disclosed
EP-3214086-B1 SUBSTITUTED DIHYDROPYRROLOPYRAZOLE COMPOUND UBE INDUSTRIES (JP) 2021-09-22 EP disclosed
US-10968238-B2 Substituted dihydropyrrolopyrazole compound UBE INDUSTRIES, LTD. (JP) 2021-04-06 US disclosed
EP-0755514-A1 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1997-01-29 EP disclosed
WO-1995028640-A1 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-10-26 WO disclosed
EP-0608894-A1 Positive-type photosensitive resin compositions Nippon Paint Co., Ltd. (JP) 1994-08-03 EP disclosed
CN-1087787-A Lose Nondigestible fat compositions oil, that contain less nondigestible solid particle in order to the control passivity PROCTER & GAMBLE (US) 1994-06-15 CN disclosed
EP-0586699-A1 METHOD FOR FORMING FIXED IMAGES Kao Corporation (JP) 1994-03-16 EP disclosed
WO-1992022017-A1 METHOD FOR FORMING FIXED IMAGES KAO CORPORATION (JP) 1992-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968238-B2 Substituted dihydropyrrolopyrazole compound QDPR, CYP2D6, KCNJ11 PPARA 1437/4885PPARG 2135/4885CYP2D6 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.