SCHEMBL758770

SCHEMBL758770

CCOC(C(=O)O)c1cccc(N)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CPN1 P15169 1/20 0.53
▸ CPB2 Q96IY4 1/20 0.53
▸ PPARA Q07869 3/20 0.43
▸ PPARG P37231 1/20 0.43
▸ TP53 P04637 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ KYNU Q16719 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ PBRM1 Q86U86 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ BCHE P06276 1/20 0.37
▸ ACHE P22303 1/20 0.37
▸ MARK4 Q96L34 1/20 0.37
▸ OPRK1 P41145 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21443845 0.84 CPN1 (0.42) CPN1CPB2PPARAPPARGTP53
SCHEMBL17081174 0.84 CPN1 (0.42) CPN1CPB2PPARAPPARGTP53
SCHEMBL16589375 0.83 FFAR1 (0.45) PPARAPPARGTP53ALDH1A1
SCHEMBL1366777 0.82 CPN1 (0.53) CPN1CPB2PPARACYP3A4KYNU
SCHEMBL30573232 0.82 CPN1 (0.53) CPN1CPB2PPARACYP3A4KYNU
SCHEMBL1104877 0.82 CPN1 (0.53) CPN1CPB2PPARACYP3A4KYNU
SCHEMBL1366779 0.82 CPN1 (0.53) CPN1CPB2PPARACYP3A4KYNU
SCHEMBL2553482 0.81 PPARA (0.49) PPARAPPARGCYP3A4ALDH1A1LMNA
SCHEMBL6504745 0.81 PPARA (0.49) PPARAPPARGCYP3A4ALDH1A1LMNA
SCHEMBL17653645 0.81 PPARA (0.49) PPARAPPARGCYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180064667-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LTD (IE) 2018-03-08 — — US claimed
US-9682050-B2 Methods of treating lactose intolerance NOGRA PHARMA LIMITED (IE) 2017-06-20 — — US claimed
US-20150087678-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LIMITED (IE) 2015-03-26 — — US claimed
EP-2844242-A1 METHODS OF TREATING LACTOSE INTOLERANCE Nogra Pharma Limited (IE) 2015-03-11 — — EP claimed
WO-2013156413-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LIMITED (IE) 2013-10-24 — — WO claimed
EP-1910270-B1 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD NOGRA PHARMA LTD (IE) 2013-05-08 — — EP claimed
US-8153693-B2 Compounds for the selective treatment of the intestinal immuno-inflammatory component of the celiac disease GIULIANI INTERNATIONAL LIMITED (IE) 2012-04-10 — — US claimed
EP-2222291-B1 COMPOUNDS FOR THE SELECTIVE TREATMENT OF THE INTESTINAL IMMUNO-INFLAMMATORY COMPONENT OF THE CELIAC DISEASE GIULIANI INT LTD (IE) 2012-03-21 — — EP claimed
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants NOGRA PHARMA LIMITED (IE) 2011-06-23 — — US claimed
CN-101969943-A Compounds for the selective treatment of the intestinal immunoinflammatory component of celiac disease GIULIANI INT LTD 2011-02-09 — — CN claimed
US-20100305077-A1 COMPOUNDS FOR THE SELECTIVE TREATMENT OF THE INTESTINAL IMMUNO-INFLAMMATORY COMPONENT OF THE CELIAC DISEASE NOGRA PHARMA LIMITED (IE) 2010-12-02 — — US claimed
EP-2222291-A2 COMPOUNDS FOR THE SELECTIVE TREATMENT OF THE INTESTINAL IMMUNO-INFLAMMATORY COMPONENT OF THE CELIAC DISEASE Giuliani International Limited (IE) 2010-09-01 — — EP claimed
EP-2131829-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS Giuliani International Limited (IE) 2009-12-16 — — EP claimed
WO-2009080828-A2 COMPOUNDS FOR THE SELECTIVE TREATMENT OF THE INTESTINAL IMMUNO-INFLAMMATORY COMPONENT OF THE CELIAC DISEASE GIULIANI INTERNATIONAL LIMITED (IE) 2009-07-02 — — WO claimed
US-20090048343-A1 Compounds and Their Salts Specific to the PPAR Receptors and the EGF Receptors and Their Use in the Medical Field NOGRA PHARMA LIMITED (IE) 2009-02-19 — — US claimed
WO-2008104557-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS GIULIANI INTERNATIONAL LIMITED (IE) 2008-09-04 — — WO claimed
EP-1910270-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD Giuliani International Limited (IE) 2008-04-16 — — EP claimed
WO-2007010516-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD GIULIANI INTERNATIONAL LIMITED (IE) 2007-01-25 — — WO claimed
US-11753365-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2023-09-12 — — US disclosed
WO-2007010516-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD GIULIANI INTERNATIONAL LIMITED (IE) 2007-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305077-A1 COMPOUNDS FOR THE SELECTIVE TREATMENT OF THE INTESTINAL IMMUNO-INFLAMMATORY COMPONENT OF THE CELIAC DISEASE SI, FABP2, NFKBIA CPN1 150/4885CPB2 65/4885PPARA 1519/4885
US-11753365-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 CPN1 2301/4885CPB2 451/4885PPARA 648/4885
US-20150087678-A1 METHODS OF TREATING LACTOSE INTOLERANCE LCT, LPL, PPARG CPN1 696/4885CPB2 700/4885PPARA 4/4885
US-20090048343-A1 Compounds and Their Salts Specific to the PPAR Receptors and the EGF Receptors and Their Use in the Medical Field EGFR, ERBB3, FGFR3 CPN1 3318/4885CPB2 2395/4885PPARA 9/4885
US-20180064667-A1 METHODS OF TREATING LACTOSE INTOLERANCE LCT, LPL, PPARG CPN1 696/4885CPB2 700/4885PPARA 4/4885
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants PPARG, FABP2, PPARD CPN1 2091/4885CPB2 1744/4885PPARA 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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