⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249426 | 0.85 | GABRA1 (0.35) | — | |
| SCHEMBL3251620 | 0.83 | — | — | |
| SCHEMBL3249692 | 0.77 | ACE2 (0.31) | — | |
| SCHEMBL9063441 | 0.75 | ACE2 (0.34) | — | |
| SCHEMBL5547317 | 0.75 | LPAR1 (0.38) | — | |
| SCHEMBL22013194 | 0.71 | AOC1 (0.32) | — | |
| SCHEMBL3250644 | 0.71 | — | — | |
| SCHEMBL3245461 | 0.71 | L3MBTL1 (0.32) | — | |
| SCHEMBL11554595 | 0.70 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL3250855 | 0.70 | GABRA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |