Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044714 | 0.89 | METTL3 (0.50) | METTL3GAAALDH1A1MEN1KMT2A | |
| SCHEMBL3245174 | 0.85 | METTL3 (0.60) | METTL3GAAALDH1A1MAPTLMNA | |
| SCHEMBL3243820 | 0.85 | METTL3 (0.48) | METTL3GAARXFP1MAPT | |
| SCHEMBL3245198 | 0.85 | METTL3 (0.49) | METTL3GAARXFP1MRGPRX4MAPT | |
| SCHEMBL3239930 | 0.84 | METTL3 (0.47) | METTL3GAAALDH1A1RXFP1MAPT | |
| SCHEMBL3239561 | 0.84 | METTL3 (0.49) | METTL3GAARXFP1MRGPRX4MAPT | |
| SCHEMBL3241143 | 0.84 | METTL3 (0.51) | METTL3THRBGAAALDH1A1RXFP1 | |
| SCHEMBL3245303 | 0.83 | METTL3 (0.54) | METTL3GAARXFP1MAPT | |
| SCHEMBL3242335 | 0.83 | METTL3 (0.49) | METTL3GAARXFP1MAPT | |
| SCHEMBL3237348 | 0.83 | METTL3 (0.45) | METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |