Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237494 | 0.84 | CA2 (0.62) | CA2LMNAAKR1B1CA12CA1 | |
| SCHEMBL31561597 | 0.84 | CA2 (0.62) | CA2LMNAAKR1B1CA12CA1 | |
| SCHEMBL6618503 | 0.80 | CA2 (0.46) | CA2LMNAAKR1B1ALDH1A1TSHR | |
| SCHEMBL28568569 | 0.80 | CA2 (0.71) | CA2AKR1B1CA12CA1CA9 | |
| SCHEMBL29520525 | 0.80 | CA2 (0.57) | CA2LMNAAKR1B1CA12CA1 | |
| SCHEMBL4628913 | 0.77 | KMT2A (0.60) | CA2LMNAAKR1B1CA1ALDH1A1 | |
| SCHEMBL4862702 | 0.75 | CA2 (0.56) | CA2LMNAAKR1B1CA12CA1 | |
| SCHEMBL30684143 | 0.75 | CA2 (0.56) | CA2AKR1B1CA12CA1CA9 | |
| SCHEMBL8960439 | 0.75 | CA2 (0.56) | CA2AKR1B1CA12CA1CA9 | |
| SCHEMBL670176 | 0.75 | CA2 (0.56) | CA2AKR1B1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |