SCHEMBL323754

SCHEMBL323754

CCn1c(C)[c]c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.41
KDM4E B2RXH2 12/20 0.40
HTT P42858 6/20 0.40
HSD17B10 Q99714 5/20 0.40
MAPT P10636 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
NSD2 O96028 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
CYP1A2 P05177 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP2D6 P10635 1/20 0.38
HPGD P15428 7/20 0.38
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
GRIK2 Q13002 1/20 0.37
HBB P68871 1/20 0.36
POLB P06746 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10399302 0.79 CYP19A1 (0.48) ALDH1A1KDM4EHTTMAPTMEN1
SCHEMBL3093503 0.79 P2RX4 (0.40) ALDH1A1HTTMAPTMEN1KMT2A
SCHEMBL11161798 0.79 TLR8 (0.47) ALDH1A1KDM4EHTTMAPTTDP1
SCHEMBL8075668 0.78 KDM4E (0.43) ALDH1A1KDM4EHTTHSD17B10MAPT
SCHEMBL27454842 0.78 MEN1 (0.39) MAPTMEN1KMT2ATDP1NPSR1
SCHEMBL3073048 0.77 P2RX4 (0.51) ALDH1A1KDM4EHTTHSD17B10MAPT
SCHEMBL10336838 0.77 KDM4E (0.51) ALDH1A1KDM4EHTTHSD17B10MEN1
SCHEMBL11634748 0.75 KDM4E (0.53) ALDH1A1KDM4EHTTHSD17B10MEN1
SCHEMBL27889039 0.75 GALR3 (0.51) ALDH1A1KDM4EHTTMAPTMEN1
SCHEMBL700437 0.72 GPR3 (0.41) ALDH1A1KDM4EHTTHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4101540-A USEFUL FOR DYEING ACRYLONITRILE POLYMERS OR ACID-MODIFIED POLYESTERS OR POLYAMIDES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 US claimed
US-4054718-A Heat-sensitive recording material containing a malachite green color former CIBA-GEIGY CORPORATION (US) 1977-10-18 US claimed
CN-115928007-A Transfer film for forming vapor deposition mask, method for producing vapor deposition mask, and vapor deposition mask 富士胶片株式会社 2023-04-07 CN disclosed
CN-115729035-A Transfer film for vapor deposition mask formation and method for manufacturing vapor deposition mask 富士胶片株式会社 2023-03-03 CN disclosed
CN-115247252-A Transfer film for vapor deposition mask production, vapor deposition mask, and method for producing vapor deposition mask 富士胶片株式会社 2022-10-28 CN disclosed
EP-3615507-A1 THERMOCHROMIC PIGMENT COMPOSITIONS Société BIC (FR) 2020-03-04 EP disclosed
CN-106467481-B The synthetic method of indoles -3- aryl ketone derivatives 昆明学院 2019-06-25 CN disclosed
CN-105939867-B Thermal recording medium 三菱制纸株式会社 2018-05-11 CN disclosed
CN-107405910-A Negative-working lithographic printing plate precursors 伊斯曼柯达公司 2017-11-28 CN disclosed
CN-104812589-B Thermal response recording materials 普恩公司 2017-10-27 CN disclosed
CN-107267046-A A kind of thermo-chromatic and preparation method thereof, application 广东韩亚薄膜科技有限公司 2017-10-20 CN disclosed
US-4275005-A DYES FOR HEAT OR PRESSURE SENSITIVE DUPLICATION CIBA-GEIGY CORPORATION (US) 1981-06-23 US disclosed
US-4275206-A CHROMOGENS FOR RECORDING AND MARKING SYSTEMS APPLETON PAPERS INC. (US) 1981-06-23 US disclosed
US-4254032-A COLOR FORMERS FOR HEAT SENSITIVE OR PRESSURE SENSITIVE ELEMENTS CIBA-GEIGY CORPORATION (US) 1981-03-03 US disclosed
US-4232887-A PRESSURE SENSITIVE AND HEAT SENSITIVE ELEMENTS FOR RECORDING APPLETON PAPERS INC. (US) 1980-11-11 US disclosed
US-4119776-A Vinyl phthalide color formers NCR CORPORATION (US) 1978-10-10 US disclosed
US-4054718-A Heat-sensitive recording material containing a malachite green color former CIBA-GEIGY CORPORATION (US) 1977-10-18 US disclosed
US-4026883-A MACHINE READABLE AND COPIABLE NCR CORPORATION (US) 1977-05-31 US disclosed
US-4022771-A RECORD MATERIALS AND MARKING SYSTEMS NCR CORPORATION (US) 1977-05-10 US disclosed
US-4016174-A USED IN PRESSURE SENSITIVE RECORD MATERIALS AND MANIFOLD MARKING SYSTEMS NCR CORPORATION (US) 1977-04-05 US disclosed