Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073048 | 0.90 | P2RX4 (0.51) | SMN1; SMN2LMNAMEN1KMT2AP2RX4 | |
| SCHEMBL3093503 | 0.88 | P2RX4 (0.40) | CYP19A1TNFSMN1; SMN2LMNAMEN1 | |
| SCHEMBL3088631 | 0.84 | P2RX4 (0.54) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL3084394 | 0.84 | DRD2 (0.43) | TNFSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3083770 | 0.84 | TP53 (0.45) | SMN1; SMN2P2RX4TP53MAPT | |
| SCHEMBL323754 | 0.79 | ALDH1A1 (0.41) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL8356648 | 0.79 | CYP19A1 (0.46) | CYP19A1TNFSMN1; SMN2LMNAMEN1 | |
| SCHEMBL8360274 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2KMT2AMAPK1ALDH1A1NPSR1 | |
| SCHEMBL2115649 | 0.79 | CYP19A1 (0.48) | CYP19A1TNFSMN1; SMN2LMNAMEN1 | |
| SCHEMBL5622614 | 0.79 | CYP19A1 (0.48) | CYP19A1TNFSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054718-A | Heat-sensitive recording material containing a malachite green color former | CIBA-GEIGY CORPORATION (US) | 1977-10-18 | — | — | US | claimed |
| US-4966983-A | PRESSURE OR HEAT SENSITIVE ELEMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4841050-A | Carbazole containing benzopyrans | BASF AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0236973-B1 | BENZOPYRANES AND THEIR USE IN A RECORDING SYSTEM | BASF Aktiengesellschaft (DE) | 1989-06-14 | — | — | EP | disclosed |
| EP-0236973-A2 | Benzopyranes and their use in a recording system | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4054718-A | Heat-sensitive recording material containing a malachite green color former | CIBA-GEIGY CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |