Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13304628 | 0.88 | NAMPT (0.44) | LMNAGAAPKMALDH1A1CFTR | |
| SCHEMBL13292680 | 0.86 | LMNA (0.39) | LMNAGAAPKMALDH1A1CFTR | |
| SCHEMBL13303620 | 0.85 | MAPT (0.51) | LMNAGAAALDH1A1CFTRMAPT | |
| SCHEMBL13292781 | 0.85 | MAPT (0.39) | LMNAGAAPKMALDH1A1CFTR | |
| SCHEMBL13292623 | 0.85 | LMNA (0.38) | LMNAGAAPKMALDH1A1CFTR | |
| SCHEMBL13292673 | 0.83 | ALDH1A1 (0.37) | LMNAALDH1A1MAPT | |
| SCHEMBL13292672 | 0.82 | PRNP (0.36) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL14364837 | 0.82 | TDP1 (0.49) | LMNAGAAPKMALDH1A1CFTR | |
| SCHEMBL273890 | 0.82 | TDP1 (0.49) | LMNAGAAPKMALDH1A1CFTR | |
| SCHEMBL14364836 | 0.82 | TDP1 (0.49) | LMNAGAAPKMALDH1A1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745483-B2 | 2-Halofuryl-thienyl-3-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-29 | — | — | US | claimed |
| EP-1713789-B1 | 2-HALOFURYL/THIENYL-3-CARBOXAMIDES | BAYER IP GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |
| EP-1713789-B1 | 2-HALOFURYL/THIENYL-3-CARBOXAMIDES | BAYER IP GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |
| US-7745483-B2 | 2-Halofuryl-thienyl-3-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-29 | — | — | US | disclosed |
| US-7745483-B2 | 2-Halofuryl-thienyl-3-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-29 | — | — | US | disclosed |
| US-7745483-B2 | 2-Halofuryl-thienyl-3-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-29 | — | — | US | disclosed |
| US-20080064874-A1 | 2-Halofuryl/Thienyl-3-Carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | disclosed |
| US-20080064874-A1 | 2-Halofuryl/Thienyl-3-Carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | disclosed |
| US-20080064874-A1 | 2-Halofuryl/Thienyl-3-Carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | disclosed |
| EP-1713789-A1 | 2-HALOFURYL/THIENYL-3-CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005075452-A1 | 2-HALOFURYL/THIENYL-3-CARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064874-A1 | 2-Halofuryl/Thienyl-3-Carboxamides | HDHD5, HACL2, MRPL21 | LMNA 4539/4885GAA 617/4885PKM 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.