⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18475139 | 0.79 | NLRP3 (0.32) | — | |
| SCHEMBL20610821 | 0.79 | NLRP3 (0.32) | — | |
| SCHEMBL28679188 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL208497 | 0.74 | — | — | |
| SCHEMBL19661003 | 0.74 | NLRP3 (0.32) | — | |
| SCHEMBL4082528 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL1896171 | 0.72 | NLRP3 (0.31) | — | |
| SCHEMBL17038486 | 0.69 | CTSB (0.36) | — | |
| SCHEMBL48038 | 0.67 | — | — | |
| SCHEMBL4073653 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757940-B | Microbiological method for producing amides | 哥伦比亚有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2023023156-A1 | ACID CERAMIDASE INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-23 | — | — | WO | disclosed |
| EP-3710592-B1 | MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES | COLUMBIA S R L (IT) | 2022-08-31 | — | — | EP | disclosed |
| US-11261468-B2 | Microbiological process for the preparation of amides | COLUMBIA SRL (IT) | 2022-03-01 | — | — | US | disclosed |
| US-11001594-B2 | Heterocyclic modulators of HIF activity for treatment of disease | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-05-11 | — | — | US | disclosed |
| CN-111757940-A | Microbiological method for producing amides | 哥伦比亚有限公司 | 2020-10-09 | — | — | CN | disclosed |
| EP-3710592-A1 | MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES | Columbia S.r.l. (IT) | 2020-09-23 | — | — | EP | disclosed |
| US-20200248216-A1 | MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES | COLUMBIA SRL (IT) | 2020-08-06 | — | — | US | disclosed |
| US-20200248216-A1 | MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES | COLUMBIA SRL (IT) | 2020-08-06 | — | — | US | disclosed |
| US-10682419-B2 | Prodrugs of peptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| WO-1998037078-A1 | SOLID PHASE AND COMBINATORIAL SYNTHESIS OF SUBSTITUTED THIOPHENES AND OF ARRAYS OF SUBSTITUTED THIOPHENES | NOVO NORDISK A/S (DK) | 1998-08-27 | — | — | WO | disclosed |
| US-5714191-A | PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-02-03 | — | — | US | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |
| US-5608077-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-03-04 | — | — | US | disclosed |
| US-5547974-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-08-20 | — | — | US | disclosed |
| CN-1027341-C | N-Phenylpyrazole Derivative Insecticides | MAY & BAKER LTD (FR) | 1995-01-11 | — | — | CN | disclosed |
| US-5232940-A | Controlling insects, plant nematodes, helminths, protozoa | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 1993-08-03 | — | — | US | disclosed |
| US-5206372-A | PREPARATION OF 2-CHLOROPYRIDINE DERIVATIVES | SHELL RESEARCH LIMITED (GB) | 1993-04-27 | — | — | US | disclosed |
| EP-0462639-A1 | Preparation of 2-chloropyridine derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-12-27 | — | — | EP | disclosed |
| US-4231942-A | DYES OF GREENISH-YELLOW SHADES | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |