Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | GNRHR | P30968 | 15/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239684 | 0.90 | CHRM1 (0.52) | CHRM1 | |
| SCHEMBL3234282 | 0.88 | CHRM1 (0.47) | CHRM1FABP4RORC | |
| SCHEMBL3235218 | 0.88 | CHRM1 (0.44) | CHRM1FABP4RORCCYP3A4 | |
| SCHEMBL3230300 | 0.86 | CHRM1 (0.48) | CHRM1 | |
| SCHEMBL3237079 | 0.86 | CHRM1 (0.62) | CHRM1FABP4RORCGNRHRCYP3A4 | |
| SCHEMBL3230518 | 0.84 | CHRM1 (0.48) | CHRM1 | |
| SCHEMBL3234237 | 0.83 | CHRM1 (0.56) | CHRM1FABP4 | |
| SCHEMBL3233936 | 0.83 | CHRM1 (0.46) | CHRM1 | |
| SCHEMBL3236068 | 0.82 | CHRM1 (0.51) | CHRM1RORCCYP3A4 | |
| SCHEMBL3234399 | 0.82 | CHRM1 (0.63) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963271-B1 | QUINOLONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2010-07-28 | — | — | EP | claimed |