Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18641198 | 0.84 | MAPT (0.41) | OPRD1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL27653478 | 0.81 | MAPT (0.38) | OPRD1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL3261351 | 0.77 | GPR35 (0.37) | MAPTKMT2AKDM4EGLAALDH1A1 | |
| SCHEMBL1483718 | 0.75 | CSNK2A2 (0.39) | OPRD1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL2919829 | 0.73 | NPC1 (0.49) | MAPTTSHRKMT2AKDM4EL3MBTL1 | |
| SCHEMBL1483660 | 0.71 | LMNA (0.47) | OPRD1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL577650 | 0.71 | MAPT (0.45) | OPRD1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL3245224 | 0.70 | RAF1 (0.46) | MAPTL3MBTL1PKM | |
| SCHEMBL10679238 | 0.69 | OPRD1 (0.44) | OPRD1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL3239031 | 0.69 | KDM4E (0.54) | OPRD1MAPTTSHRKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022308-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010022308-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |