Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611992 | 0.80 | IDO1 (0.59) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL19760706 | 0.80 | IDO1 (0.59) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL3264403 | 0.78 | IDO1 (0.56) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL27825820 | 0.77 | IDO1 (0.58) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL29671027 | 0.77 | IDO1 (0.55) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL3613788 | 0.77 | IDO1 (0.55) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL3239320 | 0.74 | IDO1 (0.52) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL3264451 | 0.73 | ALDH1A1 (0.69) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL3262533 | 0.73 | IDO1 (0.51) | IDO1LMNAALDH1A1MAPTGAA | |
| SCHEMBL1047831 | 0.71 | ALDH1A1 (0.66) | IDO1LMNAALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015588-A1 | BENZYL-SUBSTITUTED TETRACYCLIC HETEROCYCLIC COMPOUNDS | NYCOMED GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |