Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16703049 | 0.84 | ELANE (0.41) | ELANEMAPTKDM4ELMNANPSR1 | |
| SCHEMBL2295072 | 0.81 | ELANE (0.42) | ELANEMAPTKDM4ELMNANPSR1 | |
| SCHEMBL2289818 | 0.81 | ELANE (0.42) | ELANEMAPTKDM4ELMNANPSR1 | |
| SCHEMBL3234259 | 0.80 | MMP2 (0.42) | ELANEMAPTPOLBKMT2AMMP2 | |
| SCHEMBL3239401 | 0.80 | ELANE (0.39) | ELANEMAPTKDM4ELMNANPSR1 | |
| SCHEMBL2286310 | 0.79 | ELANE (0.41) | ELANEMAPTKDM4ELMNANPSR1 | |
| SCHEMBL2287443 | 0.76 | AKR1C3 (0.37) | ELANEMAPTKDM4ELMNANPSR1 | |
| SCHEMBL25639011 | 0.75 | MTNR1A (0.45) | LMNAALDH1A1SMN1; SMN2CA2 | |
| SCHEMBL9351782 | 0.75 | MEN1 (0.50) | ELANEMAPTKDM4ELMNANPSR1 | |
| SCHEMBL10434505 | 0.74 | AKR1C3 (0.36) | ELANEMAPTKDM4ELMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017504-A1 | METHODS OF SYNTHESIZING 1-(ACYLOXY)-ALKYL CARBAMATE PRODRUGS | XENOPORT, INC. (US) | 2010-02-11 | — | — | WO | disclosed |