Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294329 | 0.82 | PTGS2 (0.44) | MMP2MMP9MMP14PTGS2POLB | |
| SCHEMBL2294327 | 0.82 | PTGS2 (0.44) | MMP2MMP9MMP14PTGS2POLB | |
| SCHEMBL16702992 | 0.81 | CA2 (0.50) | MMP2MMP9MMP14PTGS2POLB | |
| SCHEMBL3234247 | 0.80 | PTGS2 (0.42) | MMP2MMP9MMP14PTGS2POLB | |
| SCHEMBL3239407 | 0.80 | ELANE (0.40) | MMP2MMP9MMP14POLBMAPT | |
| SCHEMBL2288260 | 0.80 | PTGS2 (0.45) | MMP2MMP9MMP14PTGS2POLB | |
| SCHEMBL2291204 | 0.75 | PTGS2 (0.40) | MMP2MMP9MMP14PTGS2POLB | |
| SCHEMBL3274519 | 0.75 | PTGS2 (0.40) | MMP2MMP9MMP14PTGS2POLB | |
| SCHEMBL16703079 | 0.74 | PTGS2 (0.48) | MMP2MMP9MMP14PTGS2POLB | |
| SCHEMBL25639011 | 0.74 | MTNR1A (0.45) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017504-A1 | METHODS OF SYNTHESIZING 1-(ACYLOXY)-ALKYL CARBAMATE PRODRUGS | XENOPORT, INC. (US) | 2010-02-11 | — | — | WO | disclosed |