Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24306252 | 0.83 | NPC1 (0.52) | ALDH1A1TDP1TSHRNPC1MAPT | |
| SCHEMBL24305968 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRNPC1MAPT | |
| SCHEMBL21327719 | 0.73 | NOS1 (0.44) | ALDH1A1 | |
| SCHEMBL6897191 | 0.71 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRMAPTHTT | |
| SCHEMBL14919250 | 0.71 | MAPT (0.40) | ALDH1A1TDP1NPC1MAPTHTT | |
| SCHEMBL5572911 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRMAPTRAB9A | |
| SCHEMBL711232 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TSHRNPC1MAPTHTT | |
| SCHEMBL4437065 | 0.70 | HSD17B10 (0.41) | ALDH1A1TDP1TSHRNPC1MAPT | |
| SCHEMBL18726334 | 0.70 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRHDAC8 | |
| SCHEMBL18649595 | 0.70 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020008-A1 | POLYMER COATINGS | POLYMERS CRC LIMITED (AU) | 2010-02-25 | — | — | WO | disclosed |
| EP-2052045-A1 | POLYMERIC COATINGS AND METHODS FOR FORMING THEM | Commonwealth Scientific and Industrial Research Organisation (AU) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008019450-A1 | POLYMERIC COATINGS AND METHODS FOR FORMING THEM | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-02-21 | — | — | WO | disclosed |