Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11575510 | 0.88 | HPRT1 (0.54) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL11508876 | 0.85 | ELANE (0.46) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL547461 | 0.81 | CA1 (0.68) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL29965319 | 0.81 | CA1 (0.68) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL3071825 | 0.81 | CA1 (0.68) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL11575541 | 0.80 | ELANE (0.46) | CA1CA2CA9PRSS1PRSS2 | |
| SCHEMBL7175789 | 0.79 | CA1 (0.65) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL29338 | 0.79 | CA1 (0.65) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL5544560 | 0.78 | CA1 (0.53) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL9639738 | 0.77 | CA1 (0.63) | CA1CA2CA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603619-A | Method for preparing aryl sulfonyl fluoride by taking aryl hydrazine hydrochloride as raw material | 上海应用技术大学 | 2021-11-05 | — | — | CN | claimed |
| CN-113603619-B | Method for preparing aryl sulfonyl fluoride by taking aryl hydrazine hydrochloride as raw material | 上海应用技术大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-113603619-A | Method for preparing aryl sulfonyl fluoride by taking aryl hydrazine hydrochloride as raw material | 上海应用技术大学 | 2021-11-05 | — | — | CN | disclosed |
| US-20210115087-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIV ROCHESTER (US) | 2021-04-22 | — | — | US | disclosed |
| US-20190241615-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER | 2019-08-08 | — | — | US | disclosed |
| EP-3475294-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | The University of Rochester (US) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017223207-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER (US) | 2017-12-28 | — | — | WO | disclosed |
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| CN-1171888-C | Substituted purine derivatives, preparation method and application | ���ĵ�˹ҩƷ�¹��ɷ�����˾ | 2004-10-20 | — | — | CN | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-4088482-A | XEROGRAPHY, PHOTOSENSITIVITY | THE DOW CHEMICAL COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-3960961-A | 4'-Fluoro-4-{[4-(phenyl)cyclohexyl]amino}butyrophenones and the salts thereof | THE UPJOHN COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241615-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | SHH, SMO, DACH1 | CA1 996/4885CA2 2173/4885CA9 2413/4885 |
| US-20210115087-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | SHH, SMO, DACH1 | CA1 996/4885CA2 2173/4885CA9 2413/4885 |
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | CA1 2629/4885CA2 1149/4885CA9 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.