Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3239147 | 0.77 | CHRNB2 (0.38) | LMNASOSTCYP2C19GAA | |
| SCHEMBL3233238 | 0.73 | CHRNB2 (0.44) | LMNASOSTCYP2C19EPHX1KMT2A | |
| SCHEMBL3237787 | 0.71 | EPHX1 (0.30) | EPHX1 | |
| SCHEMBL3241059 | 0.66 | L3MBTL1 (0.39) | SOSTEPHX1 | |
| SCHEMBL3232278 | 0.62 | CHRNB2 (0.42) | SOSTKMT2A | |
| SCHEMBL4874373 | 0.62 | EPHX1 (0.33) | EPHX1EPHX2 | |
| SCHEMBL3225870 | 0.61 | LMNA (0.44) | LMNACYP2C19KMT2AMEN1CYP2C9 | |
| SCHEMBL4635895 | 0.61 | EPHX1 (0.43) | EPHX1EPHX2 | |
| SCHEMBL29764468 | 0.61 | EPHX1 (0.38) | CYP2C19EPHX1EPHX2 | |
| SCHEMBL6415568 | 0.61 | EPHX1 (0.43) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028011-A1 | AMIDES OF DIAZABICYCLONONANES AND USES THEREOF | TARGACEPT, INC. (US) | 2010-03-11 | — | — | WO | disclosed |