Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191532 | 0.89 | PYCR1 (0.67) | PYCR1TAAR1NPC1CXCR3ALDH1A1 | |
| SCHEMBL22304838 | 0.83 | PYCR1 (0.60) | PYCR1TAAR1NPC1CXCR3ALDH1A1 | |
| SCHEMBL3240218 | 0.81 | HTT (0.44) | PYCR1ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL13232509 | 0.81 | PYCR1 (0.58) | PYCR1TAAR1NPC1CXCR3ALDH1A1 | |
| SCHEMBL3242409 | 0.81 | ALDH1A1 (0.54) | PYCR1TAAR1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3339451 | 0.81 | PYCR1 (0.58) | PYCR1TAAR1NPC1CXCR3ALDH1A1 | |
| SCHEMBL21268450 | 0.81 | ALDH1A1 (0.63) | PYCR1NPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3153174 | 0.79 | PYCR1 (0.56) | PYCR1TAAR1NPC1CXCR3ALDH1A1 | |
| SCHEMBL171946 | 0.78 | PYCR1 (0.60) | PYCR1TAAR1NPC1CXCR3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27258921 | 0.77 | PYCR1 (0.58) | PYCR1TAAR1NPC1CXCR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | CFTR, PKD1, PKD2 | PYCR1 95/4885TAAR1 2698/4885NPC1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.