Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295721 | 0.83 | TRPA1 (0.43) | TSHRTRPA1ESR1ESR2ALDH1A1 | |
| SCHEMBL1344877 | 0.81 | TSHR (0.50) | TSHRTRPA1ESR1ESR2ALDH1A1 | |
| SCHEMBL7296087 | 0.79 | CCR1 (0.42) | TSHRTRPA1ESR1ESR2ALDH1A1 | |
| SCHEMBL7284331 | 0.78 | CCR1 (0.41) | TSHRTRPA1ESR1ESR2ALDH1A1 | |
| SCHEMBL10992323 | 0.78 | GAA (0.43) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL23199874 | 0.77 | TSHR (0.52) | TSHRTRPA1ESR1ESR2ALDH1A1 | |
| SCHEMBL181368 | 0.77 | TRPA1 (0.46) | TSHRTRPA1ESR1ESR2ALDH1A1 | |
| SCHEMBL3218984 | 0.77 | ESR1 (0.38) | TSHRTRPA1ESR1ESR2HTR2A | |
| SCHEMBL1094363 | 0.77 | TSHR (0.52) | TSHRTRPA1ESR1ESR2ALDH1A1 | |
| SCHEMBL10402490 | 0.77 | TRPA1 (0.46) | TSHRTRPA1ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113433248-B | Preparation method of gas chromatographic column and chromatograph device with same | 北京科瑞麦科技有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-113433248-A | Preparation method of gas chromatographic column and chromatograph device with same | 北京科瑞麦科技有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-109698078-A | Reversible overheating protection aqueous electrolyte and its preparation method and application based on Thermo-sensitive cellulose ethers hydrogel | 天津大学 | 2019-04-30 | — | — | CN | claimed |
| CN-104894857-B | Anti-bacterial, anti-itching catalysis fibre and preparation method thereof | 浙江理工大学 | 2017-12-05 | — | — | CN | claimed |
| CN-104894878-B | Anti-bacterial, anti-itching catalysis fibre based on metal phthalocyanine and preparation method thereof | 浙江理工大学 | 2017-07-28 | — | — | CN | claimed |
| CN-106831551-A | A kind of method of the ionic liquid method synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate | 山东师范大学 | 2017-06-13 | — | — | CN | claimed |
| CN-106380782-A | Acid and alkali resistant flame-retardant sound-absorbing melamine foam material for crane and preparation method thereof | 侯明 | 2017-02-08 | — | — | CN | claimed |
| CN-106222588-A | A kind of novel high-performance powder metallurgical gear | 黄宇 | 2016-12-14 | — | — | CN | claimed |
| CN-106116296-A | A kind of high tenacity tile adhesives | 广德县中威新型材料有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-106075481-A | A kind of low viscosity medical ultrasonic coupling agent | 安徽智博新材料科技有限公司 | 2016-11-09 | — | — | CN | claimed |
| US-5276008-A | Herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| EP-0332991-B1 | Substituted triazoles | BAYER AG (DE) | 1993-11-10 | — | — | EP | claimed |
| EP-0398096-B1 | SUBSTITUTED TRIAZOLONES | BAYER AG (DE) | 1993-10-13 | — | — | EP | claimed |
| EP-0412358-B1 | 3-AMINO-5-AMINOCARBONYL-1,2,4-TRIAZOLE DERIVATIVES | BAYER AG (DE) | 1993-09-29 | — | — | EP | claimed |
| EP-0415196-B1 | SUBSTITUTED 4,5-DIAMINO-1,2,4-TRIAZOL-3-(THI)ONES | BAYER AG (DE) | 1993-03-24 | — | — | EP | claimed |
| EP-0399285-B1 | PROCESS FOR THE PREPARATION OF 3-AMINO-5-AMINOCARBONYL-1,2,4-TRIAZOLE DERIVATIVES | BAYER AG (DE) | 1992-09-30 | — | — | EP | claimed |
| US-5082490-A | HERBICIDAL SUBSTITUTED 4,5-DIAMINO-1,2,4-TRIAZOL-3-(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | claimed |
| EP-0298371-B1 | SUBSTITUTED TRIAZOLINONES | BAYER AG (DE) | 1991-10-02 | — | — | EP | claimed |
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | claimed |
| EP-0399285-A1 | Process for the preparation of 3-amino-5-aminocarbonyl-1,2,4-triazole derivatives | BAYER AG (DE) | 1990-11-28 | — | — | EP | claimed |