Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436383 | 0.92 | TRPA1 (0.41) | TRPA1LMNATSHRMIFALDH1A1 | |
| SCHEMBL28153065 | 0.89 | LMNA (0.38) | TRPA1LMNATSHRMIFALDH1A1 | |
| SCHEMBL19386831 | 0.88 | FFAR1 (0.46) | TRPA1LMNATSHRALDH1A1ESR1 | |
| SCHEMBL9451744 | 0.85 | FFAR1 (0.46) | TSHRALDH1A1NPC1RAB9AESR1 | |
| SCHEMBL953748 | 0.83 | TRPA1 (0.43) | TRPA1LMNATSHRMIFALDH1A1 | |
| SCHEMBL1344877 | 0.81 | TSHR (0.50) | TRPA1TSHRALDH1A1NPC1POLB | |
| SCHEMBL17996056 | 0.80 | ESR2 (0.40) | TSHRALDH1A1ESR1ESR2MEN1 | |
| SCHEMBL29061985 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1GAAESR1ESR2 | |
| SCHEMBL954801 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1GAAESR1ESR2 | |
| SCHEMBL1445763 | 0.79 | CCR1 (0.42) | TRPA1LMNATSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121577791-A | Gas chromatography detection method for residual quantity of 2-chloropyrrole in 5-formyl-2, 4-dimethyl-1H-pyrrole-3-carboxylic acid serving as sunitinib intermediate | 扬州市普林斯医药科技有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-119595780-A | Method for detecting residual solvent in paeonol raw material | 河北大学 | 2025-03-11 | — | — | CN | claimed |
| CN-119574737-A | Method for detecting residual solvent in 1,3, 5-trihydroxybenzene | 河北广祥制药有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-115541753-B | Dissolved precipitation-gas chromatography method for determining content of residual methylene dichloride, chloroform and carbon tetrachloride in polycarbonate | 聊城鲁西聚碳酸酯有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119492818-A | Gas chromatographic analysis method and device for perfluoro-n-propyl vinyl ether | 中昊晨光化工研究院有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-119198934-A | Method and system for detecting residual solvent of buspirone hydrochloride solvent | 武汉海特生物创新医药研究有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-119176526-A | Preparation method of sulfuryl fluoride | 万华化学集团股份有限公司 | 2024-12-24 | — | — | CN | claimed |
| CN-118937505-A | Method for analyzing isosorbide dinitrate residual solvent | 山东科源制药股份有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118795043-A | Oxaragrolidine inheritance method for detecting toxic impurities | 金陵药业股份有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-118759060-A | Method for detecting dichloromethane in polycaprolactone gel | 山东采采医疗科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-110749679-A | Detection method of trimethyl pyrazine residues | 华熙生物科技股份有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-109485757-A | A kind of polypropylene and preparation method thereof containing nitrile group | 江苏中煦聚烯烃研究院有限公司 | 2019-03-19 | — | — | CN | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |
| US-20100137636-A1 | IDENTIFICATION OF A NITRILASE FROM B. JAPONICUM BY RATIONAL GENOME MINING AND METHODS OF USE | SOUTHERN METHODIST UNIVERSITY | 2010-06-03 | — | — | US | claimed |
| WO-2007094885-A2 | IDENTIFICATION OF A NITRILASE FROM B. JAPONICUM BY RATIONAL GENOME MINING AND METHODS OF USE | SOUTHERN METHODIST UNIVERSITY (US) | 2007-08-23 | — | — | WO | claimed |
| US-20070178575-A1 | Identification Of A Nitrilase From B. Japonicum By Rational Genome Mining And Methods Of Use | SOUTHERN METHODIST UNIVERSITY | 2007-08-02 | — | — | US | claimed |
| EP-0531636-B1 | Process for preparing phenyl butyronitriles and perfumery use of 2,2-dimethyl-4-phenyl valeronitrile | INT FLAVORS & FRAGRANCES INC (US) | 1995-10-18 | — | — | EP | claimed |
| EP-0628848-A1 | ELECTROCHROMIC DEVICE | Tonen Corporation (JP) | 1994-12-14 | — | — | EP | claimed |
| EP-0531636-A1 | Process for preparing phenyl butyronitriles and perfumery use of 2,2-dimethyl-4-phenyl valeronitrile | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1993-03-17 | — | — | EP | claimed |
| US-5179222-A | Reaction of isobutyronitrile with styrene derivatives in the presence of sodium hydride and lithium diisopropylamide | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1993-01-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137636-A1 | IDENTIFICATION OF A NITRILASE FROM B. JAPONICUM BY RATIONAL GENOME MINING AND METHODS OF USE | BLVRB, BBOX1, GGH | TRPA1 3630/4885LMNA 3749/4885TSHR 4014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.