SCHEMBL3240558

SCHEMBL3240558

Nc1ccc(C2SCCCS2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
PDK1 Q15118 1/20 0.42
TXNRD1 Q16881 1/20 0.42
TXNRD3 Q86VQ6 1/20 0.42
TXNRD2 Q9NNW7 1/20 0.42
POLB P06746 1/20 0.37
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CYP19A1 P11511 2/20 0.33
SLC18A3 Q16572 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7632848 0.88 TSHR (0.44) TSHRPOLBALDH1A1KDM4ELMNA
SCHEMBL327401 0.77 ALDH1A1 (0.52) TSHRPOLBALDH1A1KDM4ELMNA
SCHEMBL9271980 0.77 MAPT (0.47) TSHRPOLBALDH1A1KDM4ELMNA
SCHEMBL6694368 0.77 NPC1 (0.44) TSHRPOLBALDH1A1KDM4ELMNA
SCHEMBL5434824 0.77 MAPT (0.44) TSHRPOLBALDH1A1KDM4ELMNA
SCHEMBL2564135 0.77 MAPT (0.47) TSHRPOLBALDH1A1KDM4ELMNA
SCHEMBL5909370 0.77 POLB (0.50) TSHRPOLBALDH1A1KDM4ELMNA
SCHEMBL24705 0.76 KDM4E (0.44) TSHRKDM4ELMNANPC1RAB9A
SCHEMBL4017099 0.74 KDM4E (0.43) TSHRKDM4ELMNANPC1RAB9A
SCHEMBL11612135 0.74 KDM1A (0.44) TSHRPOLBALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101240119-B Carbon black reacted with diazonium salts and products CABOT CORP 2011-05-11 CN disclosed
EP-1225205-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-10-06 EP disclosed
EP-1942156-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-04-14 EP disclosed
CN-101240119-A Carbon black reacted with diazonium salts and products CABOT CORP (US) 2008-08-13 CN disclosed
EP-1942156-A1 Carbon black reacted with diazonium salts and products Cabot Corporation (US) 2008-07-09 EP disclosed
CN-100351320-C Carbon black reacted with diazols, and products CABOT CORP (US) 2007-11-28 CN disclosed
US-7294185-B2 In absence of exterior applies electrical current; wear resistance CABOT CORPORATION (US) 2007-11-13 US disclosed
EP-0799281-B2 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2006-03-29 EP disclosed
US-20050034629-A1 In absence of exterior applies electrical current; wear resistance BELMONT JAMES A (US) 2005-02-17 US disclosed
US-6740151-B2 IN THE ABSENCE OF AN EXTERNALLY APPLIED ELECTRIC CURRENT SUFFICIENT TO REDUCE THE DIAZONIUM SALT AND ATTACH AN ORGANIC GROUP; IMPROVED ABRASION RESISTANCE. CABOT CORPORATION 2004-05-25 US disclosed
CN-1088730-C Carbon black reacted with diazonium salts and products CABOT CORP (US) 2002-08-07 CN disclosed
EP-0799281-B1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2002-07-24 EP disclosed
EP-1225205-A2 Carbon black reacted with diazonium salts and products CABOT CORPORATION (US) 2002-07-24 EP disclosed
CN-1321708-A Carbon black reacted with diazols, and products CABOT CORP (US) 2001-11-14 CN disclosed
US-6042643-A AS PIGMENT TO COLOR PLASTICS, PAPER, TEXTILE, RUBBER, AQUEOUS INKS CABOT CORPORATION (US) 2000-03-28 US disclosed
US-5900029-A COLORING FIBER OR TEXTILE CABOT CORPORATION (US) 1999-05-04 US disclosed
US-5851280-A Reaction of carbon black with diazonium salts, resultant carbon black products and their uses CABOT CORPORATION (US) 1998-12-22 US disclosed
CN-1175270-A Carbon black reacted with diazonium salts and products CABOT CORP (US) 1998-03-04 CN disclosed
EP-0799281-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1997-10-08 EP disclosed
WO-1996018688-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1996-06-20 WO disclosed