Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LIG1 | P18858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612852 | 0.91 | MAPT (0.50) | MAPTHTR3APOLBKMT2ALMNA | |
| SCHEMBL7632848 | 0.88 | TSHR (0.44) | MAPTTSHRPOLBKMT2ALMNA | |
| SCHEMBL9778855 | 0.84 | MAOB (0.49) | MAPTLMNAKDM4EHTR2AALDH1A1 | |
| SCHEMBL9778594 | 0.80 | MAOB (0.51) | MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL6694368 | 0.77 | NPC1 (0.44) | MAPTTSHRPOLBMEN1KMT2A | |
| SCHEMBL9271980 | 0.77 | MAPT (0.47) | MAPTTSHRPOLBKMT2ALMNA | |
| SCHEMBL3240558 | 0.77 | TSHR (0.42) | MAPTTSHRPOLBMEN1KMT2A | |
| SCHEMBL327401 | 0.77 | ALDH1A1 (0.52) | MAPTTSHRPOLBMEN1KMT2A | |
| SCHEMBL2564135 | 0.77 | MAPT (0.47) | MAPTTSHRPOLBLMNACYP2A6 | |
| SCHEMBL5909370 | 0.77 | POLB (0.50) | MAPTTSHRPOLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504474-A | Preparation method of phenyl ketone amide compound | 淮北师范大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-117603183-A | 1,3-dithiane modified alpha, beta-unsaturated derivative and preparation method thereof | 兰州大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-117069645-A | Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide | 兰州大学 | 2023-11-17 | — | — | CN | disclosed |
| US-20230183167-A1 | VISIBLE LIGHT ACTIVE BIOMASS DERIVED PHOTOINITIATORS | BOWLING GREEN STATE UNIVERSITY (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230183167-A1 | VISIBLE LIGHT ACTIVE BIOMASS DERIVED PHOTOINITIATORS | BOWLING GREEN STATE UNIVERSITY (US) | 2023-06-15 | — | — | US | disclosed |
| WO-2021236590-A2 | VISIBLE LIGHT ACTIVE BIOMASS DERIVED PHOTOINITIATORS | BOWLING GREEN STATE UNIVERSITY (US) | 2021-11-25 | — | — | WO | disclosed |
| US-20070185169-A1 | 2-Mercapto-4,5-Diarylimidazole Derivatives and the use thereof as Cyclooxygenase Inhibitors | BEIERSDORF, AG | 2007-08-09 | — | — | US | disclosed |
| US-7223781-B2 | 2-mercapto-4,5-diarylimidazole derivatives and the use thereof as cyclooxygenase inhibitors | BEIERSDORF AG (DE) | 2007-05-29 | — | — | US | disclosed |
| CN-1594245-A | Application of ketene thioacetal derivatives as thioalcohol substituted reagent | UNIV NORTHEAST NORMAL (CN) | 2005-03-16 | — | — | CN | disclosed |
| US-20040116695-A1 | 2-Mercapto-4,5-diarylimidazole derivatives and the use thereof as cyclooxygenase inhibitors | BEIERSDORF AG (DE) | 2004-06-17 | — | — | US | disclosed |
| EP-1373217-A1 | 2-MERCAPTO-4,5-DIARYLIMIDAZOLE DERIVATIVES AND THE USE THEREOF AS CYCLOOXYGENASE INHIBITORS | Beiersdorf AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076951-A1 | 2-MERCAPTO-4,5-DIARYLIMIDAZOLE DERIVATIVES AND THE USE THEREOF AS CYCLOOXYGENASE INHIBITORS | BEIERSDORF AG (DE) | 2002-10-03 | — | — | WO | disclosed |
| US-5405866-A | Administering with cytostatic drugs to treat drug resistant tumors | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |
| US-5302727-A | For use with antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0523493-A1 | Dithianes | F. HOFFMANN-LA ROCHE AG (CH) | 1993-01-20 | — | — | EP | disclosed |
| US-4127588-A | Sulphur containing derivatives | HOFFMANN-LA ROCHE INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4073797-A | CORONARY DILATOR | HOFFMANN-LA ROCHE INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4003914-A | DITHIANE AND DISULFONE CORONARY DILATING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183167-A1 | VISIBLE LIGHT ACTIVE BIOMASS DERIVED PHOTOINITIATORS | BLVRB, GLB1, BTD | MAPT 722/4885HTR3A 2665/4885TSHR 4759/4885 |
| US-20070185169-A1 | 2-Mercapto-4,5-Diarylimidazole Derivatives and the use thereof as Cyclooxygenase Inhibitors | PTGS2, PTGES2, DHFR | MAPT 4634/4885HTR3A 1516/4885TSHR 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.