SCHEMBL327401

SCHEMBL327401

Oc1ccc(C2SCCCS2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 1/20 0.46
POLB P06746 1/20 0.41
ESR2 Q92731 12/20 0.39
KDM4E B2RXH2 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
LMNA P02545 2/20 0.37
CYP3A4 P08684 3/20 0.36
MAPT P10636 2/20 0.36
KDM1A O60341 1/20 0.36
MEN1 O00255 1/20 0.36
CA12 O43570 1/20 0.36
GMNN O75496 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
TYR P14679 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12471594 0.91 ALDH1A1 (0.55) ALDH1A1GAATSHRPOLBESR2
SCHEMBL7632848 0.88 TSHR (0.44) ALDH1A1GAATSHRPOLBKDM4E
SCHEMBL6694368 0.77 NPC1 (0.44) ALDH1A1TSHRPOLBKDM4ENPC1
SCHEMBL3240558 0.77 TSHR (0.42) ALDH1A1GAATSHRPOLBKDM4E
SCHEMBL9271980 0.77 MAPT (0.47) ALDH1A1GAATSHRPOLBKDM4E
SCHEMBL5434824 0.77 MAPT (0.44) ALDH1A1TSHRPOLBKDM4ENPC1
SCHEMBL2564135 0.77 MAPT (0.47) ALDH1A1TSHRPOLBKDM4ENPC1
SCHEMBL5909370 0.77 POLB (0.50) ALDH1A1GAATSHRPOLBKDM4E
SCHEMBL8064824 0.77 TSHR (0.58) ALDH1A1GAATSHRPOLBKDM4E
SCHEMBL21280037 0.75 TSHR (0.45) ALDH1A1TSHRESR2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240261201-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY CONOPCO, INC., D/B/A UNILEVER (US) 2024-08-08 US claimed
CN-101360715-A Novel 2-amino-imidazole-4-one compounds and their use in the manufacture of a medicament to be used in the treatment of cognitive impairment, alzheimer's disease, neurodegeneration and dementia ASTRAZENECA AB (SE) 2009-02-04 CN claimed
JP-9328411-A None JP disclosed
EP-4661834-A1 A PERSONAL CARE COMPOSITION Unilever IP Holdings B.V. (NL) 2025-12-17 EP disclosed
EP-4615989-A1 METHOD FOR PRODUCING EPIGALLOCATECHIN GALLATE MONOGLUCOSIDE Givaudan SA (CH) 2025-09-17 EP disclosed
EP-4604907-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY Unilever IP Holdings B.V. (NL) 2025-08-27 EP disclosed
WO-2025098792-A1 USE OF A SKIN BENEFIT AGENT IN RESTORING SKIN'S BARRIER FUNCTION UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
WO-2025098825-A1 A PERSONAL CARE COMPOSITION AND A METHOD OF TREATING SKIN UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
WO-2025098793-A1 USE OF A SKIN BENEFIT AGENT IN BOOSTING SKIN'S NIGHT REPAIR FUNCTION UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
CN-119925222-A Blue-light-resistant skin care composition containing anthrus extract and application thereof 天津尚美化妆品有限公司 2025-05-06 CN disclosed
CN-119656079-A Blue-light-resistant skin care composition containing anthrus extract and application thereof 天津尚美化妆品有限公司 2025-03-21 CN disclosed
US-5770731-A PROTECTING GROUPS, ANTIBODY DIRECTED ENZYME/PRODRUG THERAPY, ANTICARCINOGENIC AGENTS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1998-06-23 US disclosed
US-5728868-A Prodrugs of protein tyrosine kinase inhibitors CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1998-03-17 US disclosed
JP-H09328411-A SKIN LOTION MIKIMOTO PHARMACEUT CO LTD 1997-12-22 JP disclosed
EP-0708660-A1 PRODRUGS OF PROTEIN TYROSINE KINASE INHIBITORS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1996-05-01 EP disclosed
US-5393776-A Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia BRISTOL-MYERS SQUIBB COMPANY (US) 1995-02-28 US disclosed
WO-1995002420-A2 PRODRUGS OF PROTEIN TYROSINE KINASE INHIBITORS CANCER RESEARCH CAMPAIGN TECHNOLOGY LTD. (GB) 1995-01-26 WO disclosed
EP-0571928-A1 Acyclic Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia Bristol-Myers Squibb Company (US) 1993-12-01 EP disclosed
EP-0476493-A1 Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia Bristol-Myers Squibb Company (US) 1992-03-25 EP disclosed
US-4661611-A PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1987-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240261201-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY CUTA, ERCC4, FIBP ALDH1A1 919/4885GAA 1436/4885TSHR 4648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.