Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432230 | 0.84 | HPGD (0.60) | MAPTALDH1A1CYP3A4GAAHPGD | |
| SCHEMBL4788083 | 0.84 | HPGD (0.60) | MAPTALDH1A1CYP3A4GAAHPGD | |
| SCHEMBL8252108 | 0.84 | HPGD (0.66) | LMNAMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL4929420 | 0.83 | HPGD (0.53) | LMNAALDH1A1HPGDRAB9APOLB | |
| SCHEMBL5864338 | 0.79 | PLA2G1B (0.57) | LMNAALDH1A1GAAHPGDRAB9A | |
| SCHEMBL6431910 | 0.79 | PLA2G1B (0.57) | LMNAALDH1A1GAAHPGDRAB9A | |
| SCHEMBL21845943 | 0.76 | ALDH1A1 (0.55) | LMNAMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL7430897 | 0.76 | ALDH1A1 (0.59) | LMNAMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL3240744 | 0.76 | ALDH1A1 (0.55) | LMNAMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL1286079 | 0.75 | CYP3A4 (0.54) | LMNAMAPTMAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024772-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-04 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |