Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141942 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPK1MAPTKDM4E | |
| SCHEMBL4746745 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4743831 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4747913 | 0.83 | RECQL (0.62) | ALDH1A1LMNAMAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL2695687 | 0.79 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPK1MAPTKDM4E | |
| SCHEMBL3240749 | 0.76 | LMNA (0.55) | ALDH1A1LMNAMAPK1MAPTCYP3A4 | |
| SCHEMBL12707584 | 0.75 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPK1MAPTKDM4E | |
| SCHEMBL7960109 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPK1MAPTKDM4E | |
| SCHEMBL6929919 | 0.75 | RECQL (0.62) | ALDH1A1LMNAMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL28454208 | 0.74 | ALDH1A1 (0.72) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024772-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-04 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |