Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 10/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499925 | 0.84 | CRBN (0.45) | MKNK1MKNK2CA12CA1CA2 | |
| SCHEMBL667853 | 0.76 | ESR1 (0.42) | ALDH1A1NPC1TP53HPGDNFKB1 | |
| SCHEMBL30594257 | 0.72 | MAOB (0.39) | ALDH1A1KDM4ENPC1LMNAGAA | |
| SCHEMBL1002578 | 0.70 | CA2 (0.67) | MKNK1MKNK2CA12CA1CA2 | |
| SCHEMBL28896993 | 0.68 | CLK4 (0.44) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6070922 | 0.68 | — | — | |
| Terephthalamide SCHEMBL23774 | 0.67 | PARP1 (0.71) | CA12CA1CA2CA9CA14 | |
| SCHEMBL15748062 | 0.66 | MKNK1 (0.53) | MKNK1MKNK2IKBKBCA12CA1 | |
| SCHEMBL13617393 | 0.66 | MKNK1 (0.62) | MKNK1MKNK2CA12CA1CA2 | |
| SCHEMBL28610546 | 0.66 | CA2 (0.56) | MKNK1MKNK2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | disclosed |
| EP-4387451-A1 | ORAL FELINE FEED AND METHODS FOR CONTROLLING TICK INFESTATIONS IN A FELINE | In the Bowl Animal Health, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| US-20240165085-A1 | ORAL FELINE FEED AND METHODS FOR CONTROLLING TICK INFESTATIONS IN A FELINE | IN THE BOWL ANIMAL HEALTH, INC. | 2024-05-23 | — | — | US | disclosed |
| US-20240156789-A1 | ORAL FELINE FEED AND METHODS FOR CONTROLLING FLEA INFESTATIONS IN A FELINE | IN THE BOWL ANIMAL HEALTH, INC. | 2024-05-16 | — | — | US | disclosed |
| EP-4358737-A2 | ORAL FELINE FEED AND METHODS FOR CONTROLLING FLEA INFESTATIONS IN A FELINE | In the Bowl Animal Health, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117915782-A | Oral feed for felines and method for controlling flea infestations in felines | 碗中动物健康公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117769356-A | Oral feed for felines and method for controlling tick infestations in felines | 碗中动物健康公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117500498-A | Method for controlling flea and tick infestations in mammals | 碗中动物健康公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-4304357-A1 | ORAL CANINE FEED AND METHODS FOR CONTROLLING TICK INFESTATIONS IN A CANINE | In the Bowl Animal Health, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| EP-2545777-A1 | Isoxazoline compositions and their use as antiparasitics | Intervet International B.V. (NL) | 2013-01-16 | — | — | EP | disclosed |
| US-20110059988-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. | 2011-03-10 | — | — | US | disclosed |
| US-20110059988-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. | 2011-03-10 | — | — | US | disclosed |
| CN-101778566-A | Isoxazoline compositions and their use as antiparasitics | INTERVET INT BV | 2010-07-14 | — | — | CN | disclosed |
| CN-101778566-A | Isoxazoline compositions and their use as antiparasitics | INTERVET INT BV | 2010-07-14 | — | — | CN | disclosed |
| EP-2190289-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | Intervet International B.V. (NL) | 2010-06-02 | — | — | EP | disclosed |
| EP-2190289-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | Intervet International B.V. (NL) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009024541-A3 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. (NL) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009024541-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. (NL) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009024541-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. (NL) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240156789-A1 | ORAL FELINE FEED AND METHODS FOR CONTROLLING FLEA INFESTATIONS IN A FELINE | CAT, F7, PIGO | MKNK1 2599/4885MKNK2 2708/4885IKBKB 2441/4885 |
| US-20240165085-A1 | ORAL FELINE FEED AND METHODS FOR CONTROLLING TICK INFESTATIONS IN A FELINE | CAT, F7, PIGO | MKNK1 1839/4885MKNK2 1751/4885IKBKB 2437/4885 |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | PRDX5, TUBA3C, TUBA1C | MKNK1 3173/4885MKNK2 1694/4885IKBKB 3899/4885 |
| US-20110059988-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | PRDX5, TUBA3C, AADAC | MKNK1 3009/4885MKNK2 1584/4885IKBKB 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.