Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 4/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240029 | 0.94 | METTL3 (0.49) | METTL3PLA2G4ALMNAHTR1DHTR1B | |
| SCHEMBL3245711 | 0.93 | METTL3 (0.42) | METTL3TP53 | |
| SCHEMBL3243702 | 0.92 | METTL3 (0.43) | METTL3 | |
| SCHEMBL1077174 | 0.91 | METTL3 (0.58) | METTL3PLA2G4ALMNAHTR1DHTR1B | |
| SCHEMBL1077172 | 0.91 | METTL3 (0.58) | METTL3PLA2G4ALMNAHTR1DHTR1B | |
| SCHEMBL3243314 | 0.90 | METTL3 (0.53) | METTL3PLA2G4ALMNAHTR1DHTR1B | |
| SCHEMBL3243346 | 0.87 | METTL3 (0.60) | METTL3PLA2G4ALMNAHTR1DHTR1B | |
| SCHEMBL3235872 | 0.87 | METTL3 (0.50) | METTL3PLA2G4ALMNAHTR1DHTR1B | |
| SCHEMBL3241758 | 0.87 | METTL3 (0.43) | METTL3TP53 | |
| SCHEMBL3239770 | 0.86 | METTL3 (0.48) | METTL3LMNACFDMAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |