Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240012 | 0.91 | CNR2 (0.35) | LMNATHRBSMN1; SMN2HAT1EP300 | |
| SCHEMBL3245708 | 0.89 | CNR2 (0.37) | LMNATHRBSMN1; SMN2HAT1EP300 | |
| SCHEMBL3243769 | 0.89 | SLC22A12 (0.40) | LMNATHRBSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL1043649 | 0.87 | ALDH1A1 (0.42) | LMNASMN1; SMN2HAT1EP300ALDH1A1 | |
| SCHEMBL3239586 | 0.87 | MAPT (0.39) | LMNATHRBSMN1; SMN2HAT1EP300 | |
| SCHEMBL3245353 | 0.82 | CNR2 (0.41) | LMNATHRBSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL3241690 | 0.82 | THRB (0.40) | LMNATHRBSMN1; SMN2TP53CNR2 | |
| SCHEMBL3234940 | 0.81 | METTL3 (0.44) | LMNATHRBSMN1; SMN2HAT1EP300 | |
| SCHEMBL3239637 | 0.81 | SLC22A12 (0.39) | LMNAALDH1A1TP53CNR2MAPT | |
| SCHEMBL3245177 | 0.81 | MAPT (0.40) | LMNATHRBSMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |