Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 5/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244919 | 0.79 | FYN (0.50) | — | |
| SCHEMBL966493 | 0.72 | EPHX1 (0.59) | GRIN2BAURKANR1H3 | |
| SCHEMBL30496803 | 0.72 | EPHX1 (0.59) | GRIN2BAURKANR1H3 | |
| SCHEMBL5677385 | 0.72 | EPHB4 (0.46) | ICMT | |
| SCHEMBL31217239 | 0.71 | EGFR (0.44) | RXRARXRBRXRG | |
| SCHEMBL27160775 | 0.68 | NR3C2 (0.53) | AURKANR1H3 | |
| SCHEMBL10426059 | 0.67 | TP53 (0.46) | — | |
| SCHEMBL7782554 | 0.66 | EGFR (0.45) | RXRARXRBRXRG | |
| SCHEMBL23296145 | 0.66 | RXRA (0.58) | RXRARXRBRXRGGRIN2BGRIN1 | |
| SCHEMBL15782613 | 0.66 | ICMT (0.55) | ICMTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |