Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.50 |
| ▸ | SYK | P43405 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | MAPK15 | Q8TD08 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246389 | 0.79 | CTSC (0.58) | FYNSYKKDRMPOTEK | |
| SCHEMBL3241750 | 0.79 | RXRA (0.43) | — | |
| SCHEMBL3247981 | 0.76 | PTGS1 (0.61) | KDRTEKCDK8BRAFLCK | |
| SCHEMBL30022965 | 0.73 | RXFP1 (0.69) | TP53MPORXFP1 | |
| SCHEMBL505220 | 0.73 | RXFP1 (0.69) | TP53MPORXFP1 | |
| SCHEMBL31217239 | 0.71 | EGFR (0.44) | TP53 | |
| SCHEMBL3246808 | 0.71 | CTSC (0.64) | SYKKDRMPOTEKCDK8 | |
| SCHEMBL11232425 | 0.71 | FYN (0.58) | FYNTP53USP7CHEK2RXFP1 | |
| SCHEMBL6259141 | 0.70 | FYN (0.55) | FYNKDRMPOCDK8RXFP1 | |
| SCHEMBL2648798 | 0.70 | FYN (0.54) | FYNTP53USP7CHEK2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |