Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821894 | 0.91 | HPGD (0.47) | HPGDKDM4EDRD1DRD4DRD5 | |
| SCHEMBL3242889 | 0.89 | KDM4E (0.47) | CD274NPC1RAB9APRKAB2PRKAG1 | |
| SCHEMBL18810223 | 0.85 | HRH3 (0.49) | KDM4ESIGMAR1 | |
| SCHEMBL19291998 | 0.79 | CD274 (0.53) | CD274NPC1RAB9ASRCABL1 | |
| SCHEMBL210577 | 0.79 | LTA4H (0.63) | NPC1RAB9AHPGDKDM4ELTA4H | |
| SCHEMBL18259694 | 0.79 | LTA4H (0.60) | MCHR1KDRKDM4EDRD1DRD4 | |
| Hydrochloric Acid SCHEMBL5692401 | 0.78 | NPC1 (0.63) | NPC1RAB9AHPGDKDM4ELTA4H | |
| SCHEMBL3247613 | 0.77 | NPC1 (0.53) | NPC1RAB9APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL3249454 | 0.77 | KDR (0.57) | CD274NPC1RAB9AHPGDKDR | |
| SCHEMBL55617 | 0.75 | SIGMAR1 (0.48) | NPC1RAB9AKDM4EDRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |