Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 3/20 | 0.53 |
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.46 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256254 | 0.84 | KDR (0.57) | KDRFYNSYKATRNPC1 | |
| Hydrochloric Acid SCHEMBL1257055 | 0.83 | KDR (0.56) | KDRFYNSYKATRNPC1 | |
| SCHEMBL1256249 | 0.81 | KDR (0.54) | KDRFYNATRNPC1RAB9A | |
| SCHEMBL3243091 | 0.80 | CYP1A2 (0.64) | KDRFYNATRNPC1RAB9A | |
| SCHEMBL4061161 | 0.78 | LMNA (0.49) | NPC1RAB9AKDM4ELMNAMAPT | |
| SCHEMBL3241792 | 0.77 | CD274 (0.49) | KDRNPC1RAB9ACD274KDM4E | |
| SCHEMBL1257160 | 0.77 | KDR (0.50) | KDRFYNATRNPC1RAB9A | |
| SCHEMBL21064292 | 0.77 | KDR (0.55) | KDRFYNSYKATRNPC1 | |
| SCHEMBL13771534 | 0.76 | ABL1 (0.70) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2961915 | 0.76 | BACE1 (0.51) | KDRFYNATRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |