SCHEMBL324198

SCHEMBL324198

CCCCCCC(=Cc1ccc(OC)cc1CC)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 3/20 0.48
ALOX5 P09917 5/20 0.47
PTGES O14684 4/20 0.47
PPARG P37231 3/20 0.47
PSEN1 P49768 1/20 0.43
CNR1 P21554 3/20 0.43
EPHX2 P34913 2/20 0.42
MTNR1A P48039 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8436475 0.84 ALOX5 (0.43) ALOX5PTGESPPARGCNR1
SCHEMBL9301856 0.80 APEX1 (0.53) APEX1ALOX5PTGESPPARGCNR1
SCHEMBL39941 0.80 APEX1 (0.53) APEX1ALOX5PTGESPPARGCNR1
SCHEMBL2489081 0.80 APEX1 (0.53) APEX1ALOX5PTGESPPARGCNR1
SCHEMBL2490383 0.79 ALOX5 (0.54) APEX1ALOX5PTGESPPARGCNR1
SCHEMBL5319431 0.79 MEN1 (0.53) APEX1ALOX5PTGESPPARGEPHX2
SCHEMBL7824349 0.75 PTGES (0.55) APEX1ALOX5PTGESPPARG
SCHEMBL7824347 0.75 PTGES (0.55) APEX1ALOX5PTGESPPARG
SCHEMBL38662595 0.75 APEX1 (0.48) APEX1ALOX5PTGESPPARGEPHX2
SCHEMBL6367852 0.74 ALOX5 (0.58) APEX1ALOX5PTGESPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040219115-A1 Cosmetic composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-11-04 US claimed
WO-2004066973-A1 SKIN LIGHTENING COMPOSITION UNILEVER PLC (GB) 2004-08-12 WO claimed
US-20210106507-A1 METHOD OF INCREASING DURABILITY OF OIL-IN-WATER EMULSION MAKEUP SHISEIDO COMPANY, LTD. (JP) 2021-04-15 US disclosed
US-10894875-B2 Films and unit dose articles comprising aversive UV-protective agents, and uses and methods related thereto THE PROCTER & GAMBLE COMPANY (US) 2021-01-19 US disclosed
EP-2591082-B1 COMPOSITIONS COMPRISING OPTICAL BENEFIT AGENTS UNILEVER PLC (GB) 2020-11-18 EP disclosed
EP-3498812-B1 FILMS AND UNIT DOSE ARTICLES COMPRISING AVERSIVE UV-PROTECTIVE AGENTS, AND USES AND METHODS RELATED THERETO PROCTER & GAMBLE (US) 2020-06-17 EP disclosed
US-20200069541-A1 OIL-IN-WATER TYPE EMULSION COMPOSITION SHISEIDO COMPANY, LTD. (JP) 2020-03-05 US disclosed
EP-3613409-A1 METHOD FOR PRODUCING ULTRAVIOLET PROTECTION COATING FILM Kao Corporation (JP) 2020-02-26 EP disclosed
US-20190262252-A1 OIL BASED COMPOSITION AND OIL BASED COSMETIC SHISEIDO COMPANY, LTD. (JP) 2019-08-29 US disclosed
EP-3530264-A1 OIL-IN-WATER-TYPE EMULSION COMPOSITION Shiseido Company, Ltd. (JP) 2019-08-28 EP disclosed
US-20190185637-A1 FILMS AND UNIT DOSE ARTICLES COMPRISING AVERSIVE UV-PROTECTIVE AGENTS, AND USES AND METHODS RELATED THERETO THE PROCTER & GAMBLE COMPANY 2019-06-20 US disclosed
US-5919751-A ADDITIONAL BENEFIT, OTHER THAN MERELY SOFTENING OR PERFUMING THE FABRIC. WATER INSOLUBLE OIL CATIONIC QUATERNARY AMMONIUM COMPOUND, SULPHONATE, PHOSPHATE OR COMPOUND HAVING A MOLECULAR WEIGHT GREATER THAN 1000 LEVER BROTHERS COMPANY (US) 1999-07-06 US disclosed
EP-0912673-A1 FABRIC CONDITIONING COMPOSITION UNILEVER PLC (GB) 1999-05-06 EP disclosed
EP-0570230-B1 External preparation for skin SHISEIDO CO LTD (JP) 1998-09-30 EP disclosed
EP-0846461-A1 OIL-IN-WATER EMULSION COMPOSITION AND OIL-IN-WATER EMULSIFIER SHISEIDO COMPANY LIMITED (JP) 1998-06-10 EP disclosed
WO-1997044424-A1 FABRIC CONDITIONING COMPOSITION UNILEVER PLC (GB) 1997-11-27 WO disclosed
US-5580549-A BLEACHING; 2-HYDROXYBENZOIC ACID COMPOUND SHISEIDO CO., LTD. (JP) 1996-12-03 US disclosed
EP-0570230-A1 External preparation for skin SHISEIDO COMPANY LIMITED (JP) 1993-11-18 EP disclosed
US-5247121-A Cosmetics L'OREAL (FR) 1993-09-21 US disclosed
US-5112601-A Cosmetics L'OREAL (FR) 1992-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210106507-A1 METHOD OF INCREASING DURABILITY OF OIL-IN-WATER EMULSION MAKEUP CUTA, LIPA, POLI APEX1 1061/4885ALOX5 70/4885PTGES 316/4885
US-20200069541-A1 OIL-IN-WATER TYPE EMULSION COMPOSITION LIPA, CUTA, FAM83A APEX1 4021/4885ALOX5 74/4885PTGES 493/4885
US-10894875-B2 Films and unit dose articles comprising aversive UV-protective agents, and uses and methods related thereto UBXN1, UBXN4, UBQLN1 APEX1 619/4885ALOX5 1543/4885PTGES 3207/4885
US-20190185637-A1 FILMS AND UNIT DOSE ARTICLES COMPRISING AVERSIVE UV-PROTECTIVE AGENTS, AND USES AND METHODS RELATED THERETO UBXN1, UBXN4, UBQLN1 APEX1 619/4885ALOX5 1543/4885PTGES 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.