Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.34 |
| ▸ | RORC | P51449 | 5/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239605 | 0.90 | METTL3 (0.41) | METTL3SLC22A12P2RX7RXFP1MAPT | |
| SCHEMBL3246498 | 0.89 | METTL3 (0.40) | METTL3SLC22A12RXFP1MAPTGAA | |
| SCHEMBL3235851 | 0.89 | METTL3 (0.39) | METTL3SLC22A12RXFP1MAPTGAA | |
| SCHEMBL1045938 | 0.88 | METTL3 (0.44) | METTL3P2RX7RORCRXFP1MAPT | |
| SCHEMBL3241875 | 0.86 | METTL3 (0.42) | METTL3SLC22A12RXFP1MAPTGAA | |
| SCHEMBL3247219 | 0.86 | SLC22A12 (0.43) | METTL3SLC22A12MAPTCMA1 | |
| SCHEMBL3239987 | 0.86 | METTL3 (0.49) | METTL3SLC22A12P2RX7MAPTGAA | |
| SCHEMBL3245315 | 0.84 | METTL3 (0.36) | METTL3SLC22A12RORCMAPTGAA | |
| SCHEMBL3232535 | 0.84 | METTL3 (0.41) | METTL3SLC22A12P2RX7RXFP1MAPT | |
| SCHEMBL3239637 | 0.83 | SLC22A12 (0.39) | METTL3SLC22A12MAPTGAACMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |