Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235851 | 0.92 | METTL3 (0.39) | METTL3SLC22A12MAPTCMA1TP53 | |
| SCHEMBL3239605 | 0.92 | METTL3 (0.41) | METTL3SLC22A12MAPTCMA1TP53 | |
| SCHEMBL3241875 | 0.90 | METTL3 (0.42) | METTL3SLC22A12MAPTCMA1TP53 | |
| SCHEMBL3247219 | 0.90 | SLC22A12 (0.43) | METTL3SLC22A12MAPTCMA1TP53 | |
| SCHEMBL3242292 | 0.89 | METTL3 (0.39) | METTL3SLC22A12MAPTCMA1RXFP1 | |
| SCHEMBL3239987 | 0.89 | METTL3 (0.49) | METTL3SLC22A12MAPTTP53GAA | |
| SCHEMBL1043666 | 0.87 | METTL3 (0.45) | METTL3SLC22A12MAPTCMA1RXFP1 | |
| SCHEMBL3245315 | 0.87 | METTL3 (0.36) | METTL3SLC22A12MAPTCMA1TP53 | |
| SCHEMBL3232535 | 0.87 | METTL3 (0.41) | METTL3SLC22A12MAPTCMA1TP53 | |
| SCHEMBL3239637 | 0.86 | SLC22A12 (0.39) | METTL3SLC22A12MAPTCMA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |