Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235851 | 0.92 | METTL3 (0.39) | SLC22A12METTL3MAPTMCL1TP53 | |
| SCHEMBL3239987 | 0.90 | METTL3 (0.49) | SLC22A12METTL3MAPTTP53 | |
| SCHEMBL3246498 | 0.90 | METTL3 (0.40) | SLC22A12METTL3MAPTTP53CMA1 | |
| SCHEMBL3241875 | 0.89 | METTL3 (0.42) | SLC22A12METTL3MAPTTP53CMA1 | |
| SCHEMBL3239605 | 0.89 | METTL3 (0.41) | SLC22A12METTL3MAPTTP53CMA1 | |
| SCHEMBL3232535 | 0.88 | METTL3 (0.41) | SLC22A12METTL3MAPTMCL1TP53 | |
| SCHEMBL1046522 | 0.88 | SLC22A12 (0.46) | SLC22A12METTL3MAPTCMA1 | |
| SCHEMBL3242292 | 0.86 | METTL3 (0.39) | SLC22A12METTL3MAPTCMA1 | |
| SCHEMBL3245315 | 0.86 | METTL3 (0.36) | SLC22A12METTL3MAPTTP53CMA1 | |
| SCHEMBL3239637 | 0.85 | SLC22A12 (0.39) | SLC22A12METTL3MAPTTP53CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |