Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.75 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.58 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209080 | 0.86 | LOXL2 (1.00) | LOXL2UBE2TASIC3NPC1RAB9A | |
| SCHEMBL3248813 | 0.86 | LOXL2 (1.00) | LOXL2UBE2TASIC3NPC1RAB9A | |
| SCHEMBL11328940 | 0.85 | NPC1 (0.54) | LOXL2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4390136 | 0.84 | NPC1 (0.53) | LOXL2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5358557 | 0.82 | NPC1 (0.63) | LOXL2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28672134 | 0.82 | NPC1 (0.51) | LOXL2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL30513863 | 0.82 | NPC1 (0.51) | LOXL2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL16655049 | 0.82 | NPC1 (0.51) | LOXL2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28125037 | 0.82 | NPC1 (0.51) | LOXL2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3251161 | 0.80 | UBE2T (0.59) | LOXL2UBE2TASIC3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027615-B1 | ANTI-INFECTIVE COMPOUNDS | PASTEUR INSTITUT KOREA (KR) | 2021-07-21 | — | — | EP | disclosed |
| US-20160185774-A1 | Anti-Infective Compounds | INSTITUT PASTEUR KOREA (KR) | 2016-06-30 | — | — | US | disclosed |
| US-20160185774-A1 | Anti-Infective Compounds | INSTITUT PASTEUR KOREA (KR) | 2016-06-30 | — | — | US | disclosed |
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141164-A1 | New 1,2,4-triazine derivatives and biological applications thereof | Mutabilis (FR) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185774-A1 | Anti-Infective Compounds | RABGGTB, ELANE, SERPINB1 | LOXL2 3227/4885UBE2T 1536/4885ASIC3 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.