Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240187 | 0.98 | HRH3 (0.66) | HRH3ALDH1A1HRH4KDM4EMEN1 | |
| SCHEMBL3240482 | 0.87 | HRH3 (0.60) | HRH3ALDH1A1KDM4ECXCR4CYP2D6 | |
| SCHEMBL2265992 | 0.86 | HRH3 (0.78) | HRH3ALDH1A1HRH4KDM4EMEN1 | |
| SCHEMBL4429235 | 0.86 | HRH3 (0.78) | HRH3ALDH1A1HRH4KDM4EMEN1 | |
| SCHEMBL1334239 | 0.84 | HRH3 (0.75) | HRH3ALDH1A1HRH4KDM4EMEN1 | |
| SCHEMBL302270 | 0.84 | HRH3 (0.74) | HRH3ALDH1A1HRH4KDM4ECXCR4 | |
| SCHEMBL4277270 | 0.76 | HRH3 (1.00) | HRH3ALDH1A1HRH4KDM4EMEN1 | |
| SCHEMBL19582018 | 0.75 | LMNA (0.67) | HRH3ALDH1A1KDM4E | |
| SCHEMBL4764364 | 0.75 | HRH3 (0.78) | HRH3ALDH1A1HRH4KDM4EMEN1 | |
| SCHEMBL3245523 | 0.75 | NCF1 (0.55) | HRH3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | CFTR, PKD1, PKD2 | HRH3 2578/4885ALDH1A1 2115/4885HRH4 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.