SCHEMBL3243143

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13348672	0.79	ALDH1A1 (0.42)	METAP2RAB9AKMT2AKDM4EALDH1A1
	SCHEMBL12086500	0.78	CCR1 (0.54)	METAP2RAB9ACCR1CCR5KMT2A
	SCHEMBL3275027	0.75	METAP2 (0.57)	METAP2RAB9ACCR1CCR5KMT2A
	SCHEMBL4579898	0.75	CCR1 (0.50)	METAP2RAB9ACCR1CCR5KMT2A
	SCHEMBL12330452	0.75	CCR1 (0.50)	METAP2RAB9ACCR1CCR5KMT2A
	SCHEMBL27192221	0.75	CCR1 (0.50)	METAP2RAB9ACCR1CCR5KMT2A
	SCHEMBL31509691	0.75	CCR1 (0.50)	METAP2RAB9ACCR1CCR5KMT2A
	8-Hydroxy Quinaldine SCHEMBL29483489	0.72	METAP2 (1.00)	METAP2RAB9ACCR1CCR5KMT2A
	8-Hydroxy Quinaldine SCHEMBL297247	0.72	METAP2 (1.00)	METAP2RAB9ACCR1CCR5KMT2A
	SCHEMBL20247361	0.72	CCR1 (0.46)	METAP2RAB9ACCR1CCR5KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.