Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243186 | 1.00 | KCNH2 (0.53) | KCNH2SLC2A1 | |
| SCHEMBL5256973 | 0.88 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL5252383 | 0.88 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL5256971 | 0.88 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL5253585 | 0.87 | KCNH2 (0.59) | KCNH2SLC2A1 | |
| SCHEMBL3273252 | 0.85 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| SCHEMBL3272105 | 0.85 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| Oxalic Acid SCHEMBL5418955 | 0.84 | SLC2A1 (0.64) | KCNH2SLC2A1 | |
| SCHEMBL5798553 | 0.83 | KCNH2 (0.56) | KCNH2SLC2A1 | |
| SCHEMBL5657534 | 0.81 | SLC2A1 (0.55) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181996-A1 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2010-05-05 | — | — | EP | disclosed |
| US-7312212-B2 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2007-12-25 | — | — | US | disclosed |
| US-7109213-B2 | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 2006-09-19 | — | — | US | disclosed |
| US-20050159411-A1 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2005-07-21 | — | — | US | disclosed |
| US-20050085494-A1 | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 2005-04-21 | — | — | US | disclosed |
| EP-1470131-A2 | AMINOPIPERIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 2004-10-27 | — | — | EP | disclosed |
| EP-1470125-A1 | AMINOPIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064421-A1 | AMINOPIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003064431-A2 | AMINOPIPERIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085494-A1 | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them | NPEPPS, AASDHPPT, DNPEP | KCNH2 839/4885SLC2A1 3418/4885 |
| US-20050159411-A1 | Aminopiperidine derivatives | AMPD2, AMPD3, NPEPPS | KCNH2 1182/4885SLC2A1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.